SCHEMBL8585128

SCHEMBL8585128

C=CCc1ccc(O)c(C(C)=O)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
XDH P47989 1/20 0.59
GABRA1 P14867 6/20 0.58
GABRB2 P47870 6/20 0.58
ALDH1A1 P00352 3/20 0.58
CNR2 P34972 3/20 0.58
MEN1 O00255 3/20 0.58
KMT2A Q03164 3/20 0.58
GAA P10253 2/20 0.58
MAPT P10636 2/20 0.58
CNR1 P21554 2/20 0.58
HPGD P15428 2/20 0.58
NPSR1 Q6W5P4 2/20 0.58
PPARG P37231 2/20 0.58
PPARD Q03181 2/20 0.58
KDM4E B2RXH2 1/20 0.58
ALDH2 P05091 1/20 0.58
AKR1B1 P15121 1/20 0.58
ALOX5 P09917 5/20 0.54
PTGS1 P23219 2/20 0.54
CYP3A4 P08684 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL979252 0.84 KLKB1 (0.65) XDHGABRA1GABRB2ALDH1A1CNR2
SCHEMBL28834579 0.84 XDH (0.61) XDHGABRA1GABRB2ALDH1A1CNR2
SCHEMBL3900444 0.83 HTT (0.58) XDHALDH1A1MEN1KMT2AMAPT
SCHEMBL5831387 0.83 XDH (0.59) XDHGABRA1GABRB2ALDH1A1CNR2
SCHEMBL9701442 0.81 XDH (0.58) XDHGABRA1GABRB2ALDH1A1CNR2
SCHEMBL9740664 0.81 XDH (0.58) XDHGABRA1GABRB2ALDH1A1CNR2
SCHEMBL7781261 0.81 PTGS1 (0.50) XDHGABRA1GABRB2ALDH1A1CNR2
Hydroxychavicol SCHEMBL1657169 0.81 XDH (0.79) XDHGABRA1GABRB2ALDH1A1CNR2
SCHEMBL8519932 0.80 XDH (0.56) XDHGABRA1GABRB2ALDH1A1CNR2
SCHEMBL13302505 0.80 KLKB1 (0.68) ALDH1A1KMT2AGAAMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112745204-A Preparation method of aryl phenol ketone 平顶山德源精细化学品有限公司 2021-05-04 CN disclosed
EP-0706510-B1 OXIMATION PROCESS HENKEL CORP (US) 1998-10-28 EP disclosed
EP-0706510-A1 OXIMATION PROCESS HENKEL CORPORATION (US) 1996-04-17 EP disclosed
EP-0706510-A4 OXIMATION PROCESS HENKEL CORP (US) 1996-02-19 EP disclosed
US-5488161-A REACTION OF KETONE OR ALDEHYDE WITH HYDROXYLAMINE IN THE PRESENCE OF PHASE TRANSFER CATALYST, ALKYLPHENOL AND CARBOXY ACID OR BASE HENKEL CORPORATION (US) 1996-01-30 US disclosed
WO-1995001957-A1 OXIMATION PROCESS HENKEL CORPORATION (US) 1995-01-19 WO disclosed