Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.44 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.44 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.40 |
| ▸ | LPL | P06858 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.37 |
| ▸ | EEF2K | O00418 | 1/20 | 0.37 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29964468 | 0.82 | MAPT (0.50) | TNIKLIMK1MAPT | |
| SCHEMBL1947692 | 0.82 | CYP2A6 (0.44) | CYP2A6CYP2E1CYP2B6CYP17A1CYP11B1 | |
| SCHEMBL6193428 | 0.79 | — | — | |
| SCHEMBL1924747 | 0.76 | MAPT (0.57) | TNIKMAPT | |
| SCHEMBL22182001 | 0.76 | LIMK1 (0.54) | FYNTNIKLIMK1MAPT | |
| SCHEMBL2492357 | 0.75 | MAPT (0.67) | TNIKPIM1AURKBNPC1MAPT | |
| SCHEMBL8260133 | 0.75 | ALDH1A1 (0.48) | NPC1MAPT | |
| SCHEMBL16375393 | 0.75 | CYP2A6 (0.52) | FYNCYP2A6CYP2E1CYP2B6CYP17A1 | |
| SCHEMBL17680376 | 0.74 | CYP2A6 (0.47) | CYP2A6CYP2E1CYP2B6CYP17A1CYP11B1 | |
| SCHEMBL28182009 | 0.73 | CYP3A4 (0.46) | TNIKMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1251523-A | Sulfonamide derivatives | LILLY CO ELI (US) | 2000-04-26 | — | — | CN | disclosed |
| WO-1998033496-A1 | SULPHONAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1998-08-06 | — | — | WO | disclosed |