SCHEMBL8585352

SCHEMBL8585352

Cc1cn([C@@]2(C=O)C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TK1 P04183 6/20 0.42
TYMP P19971 1/20 0.39
LMNA P02545 3/20 0.39
ALB P02768 2/20 0.39
BLM P54132 2/20 0.39
ALDH1A1 P00352 1/20 0.39
POLB P06746 1/20 0.39
ADRA1A P35348 1/20 0.39
TSHR P16473 2/20 0.39
PKM P14618 1/20 0.39
PMP22 Q01453 1/20 0.39
CYP2D6 P10635 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8903799 0.91 TK1 (0.42) TK1LMNAALBBLMALDH1A1
SCHEMBL6322837 0.85 TK1 (0.38) TK1LMNAALBBLMALDH1A1
SCHEMBL31627956 0.84 TK1 (0.43) TK1LMNAALBBLMALDH1A1
SCHEMBL29364921 0.83 TK1 (0.45) TK1LMNAALBBLMALDH1A1
SCHEMBL547924 0.83 TK1 (0.43) TK1LMNAALBBLMTSHR
SCHEMBL8727960 0.83 TK1 (0.43) TK1LMNAALBBLMTSHR
SCHEMBL4809531 0.82 TK1 (0.44) TK1LMNAALBBLMALDH1A1
SCHEMBL135210 0.82 TK1 (0.44) TK1LMNAALBBLMALDH1A1
SCHEMBL16187026 0.82 TK1 (0.44) TK1LMNAALBBLMALDH1A1
SCHEMBL8438314 0.81 TK1 (0.43) TK1LMNAALBBLMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115926568-B Resin film formed of cell culture scaffold material, cell culture carrier, and cell culture container 积水化学工业株式会社 2025-05-09 CN disclosed
EP-0737201-A4 BACKBONE MODIFIED OLIGONUCLEOTIDE ANALOGS AND SOLID PHASE SYNTHESIS THEREOF ISIS PHARMACEUTICALS INC (US) 1998-12-30 EP disclosed
US-5677439-A PREVENTION GENE EXPRESSION SANOFI (FR) 1997-10-14 US disclosed
EP-0753002-A1 MODIFIED OLIGONUCLEOTIDES AND INTERMEDIATES USEFUL IN NUCLEIC ACID THERAPEUTICS AMGEN INC. (US) 1997-01-15 EP disclosed
EP-0737201-A1 BACKBONE MODIFIED OLIGONUCLEOTIDE ANALOGS AND SOLID PHASE SYNTHESIS THEREOF ISIS PHARMACEUTICALS, INC. (US) 1996-10-16 EP disclosed
EP-0541722-B1 COMPOUNDS AND METHODS FOR INHIBITING GENE EXPRESSION STERLING WINTHROP INC (US) 1995-12-20 EP disclosed
WO-1995026972-A1 MODIFIED OLIGONUCLEOTIDES AND INTERMEDIATES USEFUL IN NUCLEIC ACID THERAPEUTICS AMGEN INC. (US) 1995-10-12 WO disclosed
WO-1995018136-A1 BACKBONE MODIFIED OLIGONUCLEOTIDE ANALOGS AND SOLID PHASE SYNTHESIS THEREOF ISIS PHARMACEUTICALS, INC. (US) 1995-07-06 WO disclosed
EP-0541722-A1 COMPOUNDS AND METHODS FOR INHIBITING GENE EXPRESSION. STERLING WINTHROP INC (US) 1993-05-19 EP disclosed
WO-1992002534-A2 COMPOUNDS AND METHODS FOR INHIBITING GENE EXPRESSION STERLING DRUG, INC. (US) 1992-02-20 WO disclosed