SCHEMBL8586131

SCHEMBL8586131

CN(C)C(S)=N[N+](=O)[O-]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10354564 0.70
SCHEMBL8801608 0.70
SCHEMBL4191579 0.69
SCHEMBL8632083 0.67 KDM4E (0.30)
SCHEMBL4209002 0.67 ALDH1A1 (0.31)
SCHEMBL8632087 0.67 KDM4E (0.30)
SCHEMBL27447202 0.67 ALDH1A1 (0.31)
SCHEMBL5207939 0.65
SCHEMBL21461623 0.65
SCHEMBL8274102 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-10007648-A None JP disclosed
EP-3853202-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS ModernaTX, Inc. (US) 2021-07-28 EP disclosed
WO-2020061367-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS MODERNATX, INC. (US) 2020-03-26 WO disclosed
CN-1060615-C Guanidine derivatives, their production and insecticides TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2001-01-17 CN disclosed
JP-H107648-A PRODUCTION OF 1,2-DISUBSTITUTED-3-NITROISOTHIOUREA COMPOUND MITSUI PETROCHEM IND LTD 1998-01-13 JP disclosed