SCHEMBL8586534

SCHEMBL8586534

NP(=O)(OC(c1ccccc1)(c1ccccc1)c1ccccc1)OC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.42
PTPN1 P18031 3/20 0.40
KCNN4 O15554 2/20 0.39
LMNA P02545 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MAPK1 P28482 1/20 0.34
CA2 P00918 2/20 0.34
CA1 P00915 1/20 0.34
CA5A P35218 1/20 0.34
CA9 Q16790 1/20 0.34
MAPT P10636 1/20 0.34
KMT2A Q03164 1/20 0.34
TSHR P16473 2/20 0.33
PGK1 P00558 1/20 0.33
PGK2 P07205 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
KCNH2 Q12809 1/20 0.33
PTPN5 P54829 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1070249 0.81 PTPN1 (0.43) KIF11PTPN1KCNN4MAPK1CA2
SCHEMBL31121758 0.77 PTPN1 (0.51) KIF11PTPN1KCNN4MAPK1KMT2A
SCHEMBL5613563 0.77 PTPN1 (0.50) KIF11PTPN1KCNN4CA2CA5A
SCHEMBL1070250 0.77 PTPN1 (0.50) KIF11PTPN1KCNN4CA2CA5A
SCHEMBL28914618 0.74 KCNN4 (0.39) KIF11PTPN1KCNN4LMNAMAPK1
SCHEMBL1150576 0.72 PTPN1 (0.50) KIF11PTPN1KCNN4CA2CA5A
SCHEMBL3517707 0.71 PTPN1 (0.44) KIF11PTPN1KCNN4SMN1; SMN2CA2
SCHEMBL11032371 0.71 PTPN1 (0.44) KIF11PTPN1KCNN4SMN1; SMN2CA2
SCHEMBL30900873 0.70 KIF11 (0.36) KIF11PTPN1KCNN4KMT2ATSHR
SCHEMBL22232956 0.69 KIF11 (0.45) KIF11SMN1; SMN2MAPTKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5801045-A Collagen-like polypeptides and biopolymers and nucleic acids encoding same EASTMAN KODAK COMPANY (US) 1998-09-01 US disclosed
US-5710252-A GENETIC ENGINEERING AND POLYPEPTIDES EASTMAN KODAK COMPANY (US) 1998-01-20 US disclosed
US-5670616-A CAPABLE OF BEING STAINED WITH CATIONIC CARBOCYANINE DYE EASTMAN KODAK COMPANY (US) 1997-09-23 US disclosed
US-5580712-A CONTROLLING THE GRAIN MORPHOLOGY BY A CULTURE PRODUCT POLYPEPTIDES EASTMAN KODAK COMPANY (US) 1996-12-03 US disclosed