Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4295980 | 0.75 | L3MBTL1 (0.51) | SMN1; SMN2KMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL12190585 | 0.74 | L3MBTL1 (0.57) | SMN1; SMN2KMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL13609559 | 0.73 | CSNK2A2 (0.37) | SMN1; SMN2KMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL22532026 | 0.72 | L3MBTL1 (0.56) | SMN1; SMN2KMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL27488724 | 0.72 | L3MBTL1 (0.56) | SMN1; SMN2KMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL9075512 | 0.72 | SMN1; SMN2 (0.47) | SMN1; SMN2KMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL8403922 | 0.72 | SMN1; SMN2 (0.53) | SMN1; SMN2KMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL3933899 | 0.72 | SMN1; SMN2 (0.65) | SMN1; SMN2KMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL4295973 | 0.70 | SMN1; SMN2 (0.61) | SMN1; SMN2KMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL13609548 | 0.69 | CSNK2A2 (0.40) | SMN1; SMN2KMT2AL3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804443-A4 | NON-NUCLEOTIDE PHOSPHORUS ESTER OLIGOMERS | PHARMAGENICS INC (US) | 1998-04-29 | — | — | EP | disclosed |
| EP-0804443-A1 | NON-NUCLEOTIDE PHOSPHORUS ESTER OLIGOMERS | PHARMAGENICS, INC. (US) | 1997-11-05 | — | — | EP | disclosed |
| WO-1996022297-A1 | NON-NUCLEOTIDE PHOSPHORUS ESTER OLIGOMERS | PHARMAGENICS, INC. (US) | 1996-07-25 | — | — | WO | disclosed |