Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL717823 | 0.91 | SIGMAR1 (0.31) | SIGMAR1KDM4ELMNATP53CHRM2 | |
| SCHEMBL8056521 | 0.91 | KDM4E (0.30) | KDM4ELMNATP53CHRM2CYP3A4 | |
| SCHEMBL8057462 | 0.89 | SIGMAR1 (0.32) | SIGMAR1 | |
| SCHEMBL8532371 | 0.76 | POLB (0.34) | SIGMAR1LMNATP53NFKB1MEN1 | |
| Hydrochloric Acid SCHEMBL1996030 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL8525226 | 0.66 | — | — | |
| Hydrochloric Acid SCHEMBL1538830 | 0.66 | MEN1 (0.35) | LMNANFKB1HSD17B10MEN1KMT2A | |
| SCHEMBL29480029 | 0.65 | HTR2A (0.38) | SIGMAR1KDM4ELMNATP53CHRM2 | |
| SCHEMBL8057561 | 0.65 | KDM4E (0.35) | SIGMAR1KDM4ELMNANFKB1HSD17B10 | |
| Hydrochloric Acid SCHEMBL7646722 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741739-B1 | SYNTHESIS OF CYCLOPENTADIENYL METAL COORDINATION COMPLEXES FROM METAL HYDROCARBYLOXIDES | DOW CHEMICAL CO (US) | 1998-10-28 | — | — | EP | disclosed |