Nitric Acid

Nitric Acid

SCHEMBL8587160

Cn1sc(Cl)cc1=O.O=[N+]([O-])O.[MgH2]

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ERG11

The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KAT2B Q92831 10/20 0.44
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA9 Q16790 1/20 0.42
KDM4E B2RXH2 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
HTT P42858 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nitric Acid SCHEMBL10592026 0.98 KAT2B (0.45) KAT2BCA12CA1CA9KDM4E
Hydrochloric Acid SCHEMBL11188349 0.85 KAT2B (0.50) KAT2BCA12CA1CA9
Nitric Acid SCHEMBL14796686 0.84 KAT2B (0.39) KAT2BCA12CA1CA9
SCHEMBL5712108 0.81 KAT2B (0.44) KAT2BCA12CA1CA9
Hydrochloric Acid SCHEMBL11190142 0.81 KAT2B (0.50) KAT2BCA12CA1CA9
Hydrochloric Acid SCHEMBL11708723 0.81 KAT2B (0.50) KAT2BCA12CA1CA9
Hydrochloric Acid SCHEMBL11710311 0.81 KAT2B (0.50) KAT2BCA12CA1CA9
Hydrochloric Acid SCHEMBL410386 0.81
Hydrochloric Acid SCHEMBL11186626 0.81 KAT2B (0.50) KAT2BCA12CA1CA9
Hydrochloric Acid SCHEMBL155941 0.81 KAT2B (0.50) KAT2BCA12CA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1121413-A Antimicrobial composition SOMAR CORP (JP) 1996-05-01 CN claimed
JP-60139601-A None JP disclosed
JP-63088103-A None JP disclosed
JP-10251106-A None JP disclosed
JP-5105604-A None JP disclosed
JP-H10251106-A STABILIZED AGENT FOR EXTERMINATING HARMFUL MICROORGANISM SOMAR CORP 1998-09-22 JP disclosed
CN-1121413-A Antimicrobial composition SOMAR CORP (JP) 1996-05-01 CN disclosed
JP-H05105604-A GERMICIDAL, ALGICIDAL AND ANTISEPTIC AGENT FOR INDUSTRY JIYUNSEI KAGAKU KK 1993-04-27 JP disclosed
EP-0390371-A1 Germicidal composition SOMAR CORPORATION (JP) 1990-10-03 EP disclosed
JP-S6388103-A NOVEL ANTIMICROBIAL AGENT SOMAR CORP 1988-04-19 JP disclosed
JP-S60139601-A ANTIMICROBIAL AGENT SOMAR CORP 1985-07-24 JP disclosed
JP-S06388103-A 0001-01-01 JP disclosed