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Thioglycolic Acid

Thioglycolic Acid

SCHEMBL8587267

O=C(CS)OCC(COC(=O)CS)(COC(=O)CS)COC(=O)CS.O=C(O)CS

nearest known ligand 0.39

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Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 1/20 0.39
▸ HSD17B10 Q99714 1/20 0.39
▸ MAPK1 P28482 2/20 0.38
▸ HIF1A Q16665 2/20 0.38
▸ ALDH1A1 P00352 1/20 0.30
▸ TP53 P04637 1/20 0.30
▸ CYP3A4 P08684 1/20 0.30
▸ SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL60561 0.93 TSHR (0.43) TSHRHSD17B10MAPK1HIF1AALDH1A1
Thioglycolic Acid SCHEMBL16738053 0.88 MAPK1 (0.32) TSHRHSD17B10MAPK1HIF1A
SCHEMBL29446914 0.86 TSHR (0.39) TSHRHSD17B10MAPK1HIF1AALDH1A1
SCHEMBL99586 0.86 TSHR (0.39) TSHRHSD17B10MAPK1HIF1AALDH1A1
SCHEMBL13239258 0.82 TSHR (0.36) TSHRHSD17B10MAPK1HIF1A
SCHEMBL12301078 0.82 HSD17B10 (0.41) TSHRHSD17B10MAPK1HIF1AALDH1A1
SCHEMBL20664518 0.82 TSHR (0.46) TSHRHSD17B10MAPK1HIF1A
SCHEMBL574354 0.82 TSHR (0.36) TSHRHSD17B10MAPK1HIF1A
SCHEMBL16800392 0.82 TSHR (0.36) TSHRHSD17B10MAPK1HIF1A
SCHEMBL12395036 0.82 TSHR (0.41) TSHRHSD17B10MAPK1HIF1AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5756260-A POLYAMIC ACID ESTER, PROPYLENE GLYCOL MONOMETHYL ETHER ACETATE SUMITOMO BAKELITE COMPANY LIMITED (JP) 1998-05-26 — — US disclosed