SCHEMBL574354

SCHEMBL574354

O=C(CCS)OCC(COC(=O)CCS)(COC(=O)CCS)COC(=O)CCS.O=C(CS)OCC(COC(=O)CS)(COC(=O)CS)COC(=O)CS

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.36
HSD17B10 Q99714 1/20 0.36
MAPK1 P28482 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16800392 1.00 TSHR (0.36) TSHRHSD17B10MAPK1HIF1A
SCHEMBL12815337 1.00 TSHR (0.36) TSHRHSD17B10MAPK1HIF1A
SCHEMBL13239258 1.00 TSHR (0.36) TSHRHSD17B10MAPK1HIF1A
SCHEMBL21145630 0.94 TSHR (0.32) TSHRHSD17B10
SCHEMBL1900469 0.93 MAPK1 (0.34) MAPK1HIF1A
SCHEMBL56208 0.93 MAPK1 (0.34) MAPK1HIF1A
SCHEMBL19499879 0.91 ALDH1A1 (0.39) TSHRHSD17B10
SCHEMBL13265138 0.90 ALDH1A1 (0.41) TSHRHSD17B10MAPK1HIF1A
SCHEMBL60561 0.89 TSHR (0.43) TSHRHSD17B10MAPK1HIF1A
SCHEMBL13733257 0.88 TSHR (0.35) TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2938652-B1 POLYMERIZABLE COMPOSITION INCLUDING A BENZOXAZINE AND AN ACID-FORMING PEROXIDE CATALYST, ARTICLE, AND METHOD 3M INNOVATIVE PROPERTIES CO (US) 2021-03-31 EP disclosed
US-10882955-B2 Ammonium salt catalyzed benzoxazine polymerization 3M INNOVATIVE PROPERTIES COMPANY (US) 2021-01-05 US disclosed
EP-3512895-B1 BENZOXAZINE COMPOSITION 3M INNOVATIVE PROPERTIES CO (US) 2020-11-04 EP disclosed
EP-3233811-B1 CURABLE BENZOXAZINE COMPOSITIONS WITH IMPROVED THERMAL STABILITY 3M INNOVATIVE PROPERTIES CO (US) 2020-09-09 EP disclosed
US-10731003-B2 Benzoxazine composition 3M INNOVATIVE PROPERTIES COMPANY (US) 2020-08-04 US disclosed
US-10556991-B2 Benzoxazine and phthalonitrile resin blends 3M INNOVATIVE PROPERTIES COMPANY (US) 2020-02-11 US disclosed
EP-3512895-A1 BENZOXAZINE COMPOSITION 3M Innovative Properties Company (US) 2019-07-24 EP disclosed
US-20190169370-A1 BENZOXAZINE COMPOSITION 3M INNOVATIVE PROPERTIES COMPANY 2019-06-06 US disclosed
EP-2438107-B1 BENZOXAZINE-THIOL ADDUCTS 3M INNOVATIVE PROPERTIES CO (US) 2019-01-02 EP disclosed
US-20180312637-A1 Benzoxazine and Phthalonitrile Resin Blends 3M INNOVATIVE PROPERTIES COMPANY 2018-11-01 US disclosed
US-20110081601-A1 Nonwoven Fabric Having Cross-Linking Material CARL FREUDENBERG KG (DE) 2011-04-07 US disclosed
US-20100307680-A1 BENZOXAZINE-THIOL ADDUCTS 3M INNOVATIVE PROPERTIES COMPANY 2010-12-09 US disclosed
US-20100312004-A1 BENZOXAZINE-THIOL ADDUCTS 3M INNOVATIVE PROPERTIES COMPANY 2010-12-09 US disclosed
WO-2010141397-A1 ADHESIVE COMPOSITION BASED ON BENZOXAZINE-THIOL ADDUCTS 3M INNOVATIVE PROPERTIES COMPANY (US) 2010-12-09 WO disclosed
WO-2010141396-A1 BENZOXAZINE-THIOL ADDUCTS 3M INNOVATIVE PROPERTIES COMPANY (US) 2010-12-09 WO disclosed
US-7521015-B2 Curable thiol-ene compositions for optical articles 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-04-21 US disclosed
EP-1907428-B1 CURABLE THIOL-ENE COMPOSITIONS FOR OPTICAL ARTICLES 3M INNOVATIVE PROPERTIES CO (US) 2008-12-03 EP disclosed
EP-1907428-A1 CURABLE THIOL-ENE COMPOSITIONS FOR OPTICAL ARTICLES 3M Innovative Properties Company (US) 2008-04-09 EP disclosed
WO-2007015815-A1 CURABLE THIOL-ENE COMPOSITIONS FOR OPTICAL ARTICLES 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-02-08 WO disclosed
US-20070021521-A1 Curable thiol-ene compositions for optical articles 3M INNOVATIVE PROPERTIES COMPANY 2007-01-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100312004-A1 BENZOXAZINE-THIOL ADDUCTS AOX1, GJA1, PRDX4 TSHR 4761/4885HSD17B10 2567/4885MAPK1 4754/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.