Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC5R | P33032 | 4/20 | 0.57 |
| ▸ | MC4R | P32245 | 3/20 | 0.57 |
| ▸ | MC3R | P41968 | 2/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | MC1R | Q01726 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8586529 | 0.94 | MC4R (0.50) | MC5RMC4RMC3RHTR2AHTR2C | |
| SCHEMBL8589693 | 0.90 | MC5R (0.51) | MC5RMC4RMC3RHTR2AHTR2C | |
| SCHEMBL8589416 | 0.90 | MC4R (0.48) | MC5RMC4RMC3RHTR2AHTR2C | |
| SCHEMBL8588360 | 0.90 | MC4R (0.47) | MC5RMC4RMC3RHTR2AHTR2C | |
| SCHEMBL8589730 | 0.90 | MC4R (0.47) | MC5RMC4RMC3RHTR2AHTR2C | |
| SCHEMBL8588789 | 0.90 | MC5R (0.47) | MC5RMC4RMC3RHTR2AHTR2C | |
| SCHEMBL8586527 | 0.90 | MC4R (0.47) | MC5RMC4RMC3RHTR2AHTR2C | |
| SCHEMBL8588350 | 0.90 | MC5R (0.47) | MC5RMC4RMC3RHTR2AHTR2C | |
| SCHEMBL8588518 | 0.89 | MC5R (0.46) | MC5RMC4RMC3RHTR2AHTR2C | |
| SCHEMBL8589092 | 0.89 | MC5R (0.46) | MC5RMC4RMC3RHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998052890-A1 | 3-ARYLPROPYLAMINO NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1998-11-26 | — | — | WO | disclosed |