Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC5R | P33032 | 5/20 | 0.46 |
| ▸ | MC4R | P32245 | 3/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | MC3R | P41968 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | MC1R | Q01726 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8588360 | 0.90 | MC4R (0.47) | MC5RMC4RHTR2AHTR2CHTR2B | |
| SCHEMBL8587392 | 0.89 | MC5R (0.57) | MC5RMC4RHTR2AHTR2CHTR2B | |
| SCHEMBL8586529 | 0.86 | MC4R (0.50) | MC5RMC4RHTR2AHTR2CHTR2B | |
| SCHEMBL8589693 | 0.85 | MC5R (0.51) | MC5RMC4RHTR2AHTR2CHTR2B | |
| SCHEMBL8588518 | 0.84 | MC5R (0.46) | MC5RMC4RHTR2AHTR2CHTR2B | |
| SCHEMBL8588135 | 0.83 | CYP3A4 (0.51) | MC5RMC4RHTR2AHTR2CHTR2B | |
| SCHEMBL8586527 | 0.82 | MC4R (0.47) | MC5RMC4RHTR2AHTR2CHTR2B | |
| SCHEMBL8588350 | 0.82 | MC5R (0.47) | MC5RMC4RHTR2AHTR2CHTR2B | |
| SCHEMBL8589150 | 0.82 | TAAR1 (0.40) | SIGMAR1 | |
| SCHEMBL8587931 | 0.82 | HTR2A (0.46) | MC5RMC4RHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998052890-A1 | 3-ARYLPROPYLAMINO NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1998-11-26 | — | — | WO | disclosed |