Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 8/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.41 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.41 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8589516 | 0.80 | MEN1 (0.53) | MEN1KMT2AMAPTLMNACYP1A2 | |
| SCHEMBL8587765 | 0.74 | HTR1D (0.44) | MEN1KMT2AMAPTCYP1A2TRPV1 | |
| SCHEMBL11797724 | 0.74 | MEN1 (0.85) | MEN1KMT2AMAPTLMNAMAPK14 | |
| SCHEMBL8589281 | 0.73 | MEN1 (0.52) | MEN1KMT2AMAPTLMNACYP1A2 | |
| SCHEMBL10455797 | 0.71 | MEN1 (0.69) | MEN1KMT2AMAPTLMNACYP1A2 | |
| SCHEMBL8590451 | 0.71 | HRH3 (0.56) | MAPTLMNAHRH3TRPV1POLB | |
| SCHEMBL8589275 | 0.71 | MEN1 (0.52) | MEN1KMT2AMAPTLMNACYP1A2 | |
| SCHEMBL10710090 | 0.69 | MEN1 (0.79) | MEN1KMT2AMAPTLMNACYP1A2 | |
| SCHEMBL8619435 | 0.69 | MAPK14 (0.50) | MEN1KMT2AMAPTLMNACYP1A2 | |
| SCHEMBL10713102 | 0.69 | MEN1 (0.79) | MEN1KMT2AMAPTLMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998050346-A2 | ACETAMIDE AND UREA DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE TREATMENT OF CNS DISORDERS | SMITHKLINE BEECHAM PLC (GB) | 1998-11-12 | — | — | WO | claimed |
| WO-1998050346-A2 | ACETAMIDE AND UREA DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE TREATMENT OF CNS DISORDERS | SMITHKLINE BEECHAM PLC (GB) | 1998-11-12 | — | — | WO | disclosed |