Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 15/20 | 0.65 |
| ▸ | ADRB1 | P08588 | 13/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 10/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8587752 | 1.00 | ADRB3 (0.65) | ADRB3ADRB1ADRB2MEN1KMT2A | |
| SCHEMBL8657506 | 0.91 | ADRB3 (0.69) | ADRB3ADRB1ADRB2MEN1KMT2A | |
| SCHEMBL8586629 | 0.91 | ADRB3 (0.69) | ADRB3ADRB1ADRB2MEN1KMT2A | |
| SCHEMBL8588377 | 0.87 | ADRB3 (0.66) | ADRB3ADRB1ADRB2 | |
| SCHEMBL8588380 | 0.87 | ADRB3 (0.66) | ADRB3ADRB1ADRB2 | |
| SCHEMBL8758177 | 0.81 | ADRB3 (0.68) | ADRB3ADRB1ADRB2 | |
| SCHEMBL8587390 | 0.81 | ADRB3 (0.65) | ADRB3ADRB1ADRB2 | |
| SCHEMBL8587394 | 0.81 | ADRB3 (0.65) | ADRB3ADRB1ADRB2 | |
| SCHEMBL5433298 | 0.80 | ADRB2 (0.63) | ADRB3ADRB1ADRB2MEN1KMT2A | |
| SCHEMBL5294673 | 0.80 | ADRB2 (0.63) | ADRB3ADRB1ADRB2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998037056-A1 | PHENOXYPROPANOLAMINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SMITHKLINE BEECHAM PLC (GB) | 1998-08-27 | — | — | WO | claimed |
| WO-1998037056-A1 | PHENOXYPROPANOLAMINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SMITHKLINE BEECHAM PLC (GB) | 1998-08-27 | — | — | WO | disclosed |