Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8588905 | 0.85 | SMN1; SMN2 (0.43) | HPGDMEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL8585870 | 0.78 | HPGD (0.45) | HPGDMEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL245065 | 0.75 | NPC1 (0.46) | HPGDMEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL14169606 | 0.74 | SMN1; SMN2 (0.39) | MEN1KMT2AKDM4ERAB9ANPC1 | |
| SCHEMBL25354801 | 0.74 | NPC1 (0.40) | KDM4EL3MBTL1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL12052657 | 0.74 | ALDH1A1 (0.49) | KDM4EHSD17B10L3MBTL1RAB9ANPC1 | |
| SCHEMBL28522946 | 0.73 | KDM4E (0.46) | MEN1KMT2AKDM4EL3MBTL1RAB9A | |
| SCHEMBL28440224 | 0.72 | NPC1 (0.41) | KDM4EL3MBTL1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL29721865 | 0.71 | KDM4E (0.50) | HPGDKMT2AKDM4EHSD17B10L3MBTL1 | |
| SCHEMBL680046 | 0.71 | KDM4E (0.50) | HPGDKMT2AKDM4EHSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593868-B1 | PEG-interferon conjugates | HOFFMANN LA ROCHE (CH) | 1998-04-15 | — | — | EP | disclosed |
| US-5382657-A | Peg-interferon conjugates | HOFFMANN-LA ROCHE INC. (US) | 1995-01-17 | — | — | US | disclosed |
| EP-0593868-A1 | PEG-interferon conjugates | F. HOFFMANN-LA ROCHE AG (CH) | 1994-04-27 | — | — | EP | disclosed |