Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 2/20 | 0.46 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CCR3 | P51677 | 4/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8543189 | 1.00 | CARM1 (0.46) | CARM1PRMT6GRIN1GRIN2BGRIN2D | |
| SCHEMBL8549020 | 0.89 | GRIN2B (0.54) | CARM1PRMT6GRIN1GRIN2BGRIN2D | |
| SCHEMBL8544887 | 0.89 | CARM1 (0.46) | CARM1PRMT6GRIN1GRIN2BGRIN2D | |
| SCHEMBL8548568 | 0.89 | CARM1 (0.46) | CARM1PRMT6GRIN1GRIN2BGRIN2D | |
| SCHEMBL8873050 | 0.85 | GRIN2B (0.52) | CARM1PRMT6GRIN1GRIN2BGRIN2D | |
| SCHEMBL8547812 | 0.85 | GRIN2B (0.52) | CARM1PRMT6GRIN1GRIN2BGRIN2D | |
| SCHEMBL8542181 | 0.85 | GRIN2B (0.52) | CARM1PRMT6GRIN1GRIN2BGRIN2D | |
| SCHEMBL8544030 | 0.82 | GRIN2B (0.55) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL8542199 | 0.81 | CARM1 (0.46) | CARM1PRMT6GRIN1GRIN2BGRIN2D | |
| SCHEMBL8548529 | 0.81 | CARM1 (0.46) | CARM1PRMT6GRIN1GRIN2BGRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709384-B1 | Benzylpiperidine derivatives having high affinity for binding sites of aminoacid receptors | MERCK PATENT GMBH (DE) | 1998-12-23 | — | — | EP | disclosed |
| US-5698553-A | Benzylpiperidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-12-16 | — | — | US | disclosed |
| EP-0709384-A1 | Benzylpiperidine derivatives having high affinity for binding sites of aminoacid receptors | MERCK PATENT GmbH (DE) | 1996-05-01 | — | — | EP | disclosed |