Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRB | P23467 | 20/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13545649 | 0.94 | PTPRB (0.84) | PTPRB | |
| SCHEMBL14314330 | 0.92 | PTPRB (1.00) | PTPRB | |
| SCHEMBL468071 | 0.92 | PTPRB (1.00) | PTPRB | |
| SCHEMBL468106 | 0.92 | PTPRB (1.00) | PTPRB | |
| Ammonia Solution, Strong SCHEMBL468313 | 0.91 | PTPRB (0.98) | PTPRB | |
| Ammonia Solution, Strong SCHEMBL3578861 | 0.91 | PTPRB (0.98) | PTPRB | |
| Ammonia Solution, Strong SCHEMBL30241824 | 0.91 | PTPRB (0.98) | PTPRB | |
| SCHEMBL8554338 | 0.90 | PTPRB (0.86) | PTPRB | |
| SCHEMBL686810 | 0.89 | PTPRB (0.87) | PTPRB | |
| SCHEMBL8534739 | 0.88 | PTPRB (0.83) | PTPRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120128625-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR PREVENTING METASTASIS OF CANCER CELLS | EyePoint, Inc. | 2012-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120128625-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR PREVENTING METASTASIS OF CANCER CELLS | EPCAM, CD44, CDH1 | PTPRB 1445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.