Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.30 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.30 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.30 |
| ▸ | IARS2 | Q9NSE4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1742986 | 0.98 | LMNA (0.59) | CYP2C19HIF1ALMNAEGFRSRC | |
| SCHEMBL1744503 | 0.97 | LMNA (0.55) | CYP2C19HIF1ALMNAEGFRSRC | |
| SCHEMBL1744048 | 0.94 | LMNA (0.55) | CYP2C19HIF1ALMNAEGFRSRC | |
| SCHEMBL8587003 | 0.94 | CYP2C19 (0.65) | CYP2C19HIF1ALMNAEGFRSRC | |
| Ioforminol SCHEMBL374830 | 0.92 | LMNA (0.65) | CYP2C19HIF1ALMNAEGFRSRC | |
| SCHEMBL16883242 | 0.91 | LMNA (0.49) | CYP2C19HIF1ALMNA | |
| SCHEMBL19261519 | 0.91 | LMNA (0.54) | CYP2C19HIF1ALMNAEGFRSRC | |
| SCHEMBL2763827 | 0.90 | LMNA (0.60) | CYP2C19HIF1ALMNAEGFRSRC | |
| SCHEMBL19261520 | 0.90 | LMNA (0.51) | CYP2C19HIF1ALMNA | |
| SCHEMBL8583797 | 0.89 | CYP2C19 (0.60) | CYP2C19HIF1ALMNAEGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0855997-A4 | FORMYL DERIVATIVES AS NONIONIC CONTRAST MEDIA | BIOPHYSICA INC (US) | 1998-10-07 | — | — | EP | claimed |
| EP-0855997-A1 | FORMYL DERIVATIVES AS NONIONIC CONTRAST MEDIA | BIOPHYSICA, INC. (US) | 1998-08-05 | — | — | EP | claimed |
| WO-1997000240-A1 | FORMYL DERIVATIVES AS NONIONIC CONTRAST MEDIA | BIOPHYSICA FOUNDATION (US) | 1997-01-03 | — | — | WO | claimed |