Serine — predicted protein targets

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	PPARA	Q07869	8/20	0.46

▸	PPARG	P37231	7/20	0.44

▸	SMN1; SMN2	Q16637	1/20	0.42

▸	CTSS	P25774	6/20	0.36

▸	CTSK	P43235	5/20	0.36

▸	ACE	P12821	1/20	0.35

▸	CTSL	P07711	1/20	0.35

▸	CTSB	P07858	1/20	0.35

▸	PPARD	Q03181	2/20	0.35

▸	MAPT	P10636	1/20	0.34

▸	IDO1	P14902	1/20	0.34

▸	ITGB3	P05106	1/20	0.34

▸	ITGA2B	P08514	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Serine SCHEMBL8588277	1.00	PPARA (0.46)	PPARAPPARGSMN1; SMN2CTSSCTSK
SCHEMBL614209	0.90	PPARA (0.53)	PPARAPPARGSMN1; SMN2CTSSCTSK
SCHEMBL614208	0.90	PPARA (0.53)	PPARAPPARGSMN1; SMN2CTSSCTSK
SCHEMBL1430675	0.90	PPARA (0.53)	PPARAPPARGSMN1; SMN2CTSSCTSK
Benzoic Acid SCHEMBL9540832	0.79	PPARA (0.61)	PPARAPPARGSMN1; SMN2CTSSCTSK
SCHEMBL615910	0.78	SMN1; SMN2 (0.50)	PPARAPPARGSMN1; SMN2CTSSCTSK
SCHEMBL1604541	0.78	SMN1; SMN2 (0.50)	PPARAPPARGSMN1; SMN2CTSSCTSK
SCHEMBL615909	0.78	SMN1; SMN2 (0.50)	PPARAPPARGSMN1; SMN2CTSSCTSK
SCHEMBL2241213	0.77	SMN1; SMN2 (0.46)	PPARAPPARGSMN1; SMN2CTSSCTSK
SCHEMBL25755437	0.77	SMN1; SMN2 (0.46)	PPARAPPARGSMN1; SMN2CTSSCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-1998050030-A1	INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES	UNIVERSITY OF PITTSBURGH (US)	1998-11-12	—	—	WO	disclosed