Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 6/20 | 0.43 |
| ▸ | CTSK | P43235 | 6/20 | 0.42 |
| ▸ | CTSS | P25774 | 5/20 | 0.42 |
| ▸ | ITGAV | P06756 | 1/20 | 0.42 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 5/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2241213 | 1.00 | SMN1; SMN2 (0.46) | SMN1; SMN2PPARACTSKCTSSITGAV | |
| SCHEMBL2241216 | 1.00 | SMN1; SMN2 (0.46) | SMN1; SMN2PPARACTSKCTSSITGAV | |
| SCHEMBL1645916 | 0.92 | SMN1; SMN2 (0.45) | SMN1; SMN2PPARACTSKCTSSITGAV | |
| SCHEMBL1645920 | 0.92 | SMN1; SMN2 (0.45) | SMN1; SMN2PPARACTSKCTSSITGAV | |
| SCHEMBL25755449 | 0.92 | SMN1; SMN2 (0.45) | SMN1; SMN2PPARACTSKCTSSITGAV | |
| SCHEMBL3935163 | 0.89 | SMN1; SMN2 (0.42) | SMN1; SMN2PPARACTSKCTSSPPARG | |
| SCHEMBL28659964 | 0.88 | SMN1; SMN2 (0.48) | SMN1; SMN2CTSKCTSSCTSLCTSB | |
| SCHEMBL1644107 | 0.88 | ITGAV (0.43) | SMN1; SMN2PPARACTSKCTSSITGAV | |
| SCHEMBL7541004 | 0.88 | SMN1; SMN2 (0.48) | SMN1; SMN2CTSKCTSSCTSLCTSB | |
| SCHEMBL1644110 | 0.88 | ITGAV (0.43) | SMN1; SMN2PPARACTSKCTSSITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230210999-A1 | TARGETED PROTEASE DEGRADATION (TED) PLATFORM | EUBULUS BIOTHERAPEUTICS (HONG KONG) LIMITED (HK) | 2023-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230210999-A1 | TARGETED PROTEASE DEGRADATION (TED) PLATFORM | UCHL3, UBE2L3, ADAM33 | SMN1; SMN2 2462/4885PPARA 4777/4885CTSK 284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.