Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | SDCBP | O00560 | 1/20 | 0.35 |
| ▸ | SDC2 | P34741 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8586247 | 0.87 | MAOA (0.32) | MAOAMAOB | |
| SCHEMBL5871994 | 0.76 | MME (0.37) | — | |
| SCHEMBL8589074 | 0.72 | — | — | |
| SCHEMBL7765123 | 0.72 | KMT2A (0.40) | MEN1KMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL7318312 | 0.69 | — | — | |
| SCHEMBL8253948 | 0.68 | MAOA (0.70) | MAOASDCBPSDC2MEN1KMT2A | |
| SCHEMBL573866 | 0.67 | MAOA (0.58) | MAOASDCBPSDC2MEN1KMT2A | |
| SCHEMBL507894 | 0.66 | CYP1A2 (0.33) | MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL18719991 | 0.66 | MAOA (0.61) | MAOASDCBPSDC2MEN1KMT2A | |
| SCHEMBL4773585 | 0.66 | GBA1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0594857-B1 | METHANEDIPHOSPHONIC ACID DERIVATIVE, PRODUCTION THEREOF AND MEDICINAL USE THEREOF | TORAY INDUSTRIES (JP) | 1998-04-29 | — | — | EP | disclosed |
| US-5683992-A | TREATMENT OF RHEUMATISM, BONE DISORDERS, ANTIINFLAMMATORY, SUPPRESSION OF INTERLEUKIN-1, ANTIOXIDANT, TREATMENT OF AUTOIMMUNE DISEASES | TORAY INDUSTRIES, INC. (JP) | 1997-11-04 | — | — | US | disclosed |
| US-5527940-A | SUPPRESSES INTERLEUKIN-1 AND BONE DESTRUCTION DURING OSTEOPOROSIS; ANTIINFLAMMATORY AGENTS | TORAY INDUSTRIES, INC. (JP) | 1996-06-18 | — | — | US | disclosed |
| EP-0594857-A1 | METHANEDIPHOSPHONIC ACID DERIVATIVE, PRODUCTION THEREOF AND MEDICINAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1994-05-04 | — | — | EP | disclosed |