Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15295977 | 0.83 | TSHR (0.53) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL1320955 | 0.82 | TSHR (0.61) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL2547812 | 0.82 | TSHR (0.61) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL18290484 | 0.82 | TSHR (0.61) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL16854634 | 0.82 | TSHR (0.61) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL19862455 | 0.80 | TSHR (0.59) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL28119256 | 0.80 | TSHR (0.59) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL1192364 | 0.78 | TSHR (0.69) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL16517868 | 0.78 | TSHR (0.57) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL1463851 | 0.78 | TSHR (0.57) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8420281-B2 | Epoxy-functionalized perfluoropolyether polyurethanes | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-04-16 | — | — | US | disclosed |
| US-20120189728-A1 | METHODS AND MATERIALS FOR FABRICATING LAMINATE NANOMOLDS AND NANOPARTICLES THEREFROM | LIQUIDIA TECHNOLOGIES, INC. (US) | 2012-07-26 | — | — | US | disclosed |
| US-8128393-B2 | Methods and materials for fabricating laminate nanomolds and nanoparticles therefrom | LIQUIDIA TECHNOLOGIES, INC. (US) | 2012-03-06 | — | — | US | disclosed |
| US-20090027603-A1 | Low Surface Energy Polymeric Material for Use in Liquid Crystal Displays | NORTH CAROLINA AT CHAPEL HILL, THE UNIVERSITY OF | 2009-01-29 | — | — | US | disclosed |
| US-20080131692-A1 | Methods and materials for fabricating laminate nanomolds and nanoparticles therefrom | LIQUIDIA TECHNOLOGIES, INC. | 2008-06-05 | — | — | US | disclosed |
| WO-2007081876-A2 | NANOSTRUCTURED SURFACES FOR BIOMEDICAL/BIOMATERIAL APPLICATIONS AND PROCESSES THEREOF | LIQUIDIA TECHNOLOGIES, INC. (US) | 2007-07-19 | — | — | WO | disclosed |