SCHEMBL2547812

SCHEMBL2547812

FC(F)(F)COCC1CO1

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.61
MAPK1 P28482 1/20 0.61
ALDH1A1 P00352 9/20 0.45
SMN1; SMN2 Q16637 2/20 0.43
TDP1 Q9NUW8 3/20 0.41
TP53 P04637 4/20 0.35
CYP3A4 P08684 2/20 0.35
MAPT P10636 2/20 0.32
HPGD P15428 2/20 0.32
HIF1A Q16665 2/20 0.32
MEN1 O00255 1/20 0.32
CYP1A2 P05177 1/20 0.32
KMT2A Q03164 1/20 0.32
PPARG P37231 1/20 0.32
GLA P06280 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16854634 1.00 TSHR (0.61) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL18290484 1.00 TSHR (0.61) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL1320955 0.86 TSHR (0.61) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL19862455 0.84 TSHR (0.59) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL22385137 0.82 TSHR (0.44) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL7640985 0.82 TSHR (0.42) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL85888 0.82 TSHR (0.57) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL16517868 0.82 TSHR (0.57) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL1463851 0.82 TSHR (0.57) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL16808766 0.82 TSHR (0.57) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111793276-B Modified polypropylene material with high laser welding strength and preparation method thereof 万华化学(四川)有限公司 2023-12-19 CN claimed
CN-116376489-A Dual-curing fluorine-containing epoxy adhesive 上海本诺电子材料有限公司 2023-07-04 CN claimed
CN-113529183-B Gel preparation process of heating fiber 吉祥三宝高科纺织有限公司 2022-07-12 CN claimed
CN-114686157-A Three-dimensional reticular polymer for adhesive and preparation method thereof 江苏环峰电工材料有限公司广州分公司 2022-07-01 CN claimed
CN-113529183-A Gel preparation process of heating fiber 吉祥三宝高科纺织有限公司 2021-10-22 CN claimed
CN-111793276-A High-laser-welding-strength modified polypropylene material and preparation method thereof 万华化学(宁波)有限公司 2020-10-20 CN claimed
US-20260098032-A1 METHODS AND COMPOUNDS FOR RESTORING MUTANT p53 FUNCTION PMV PHARMACEUTICALS INC (US) 2026-04-09 US disclosed
US-20260055011-A1 AMINE-BASED SOLVENTS FOR TEMPERATURE SWING SOLVENT EXTRACTION UNIV ALABAMA (US) 2026-02-26 US disclosed
EP-4644387-A2 METHODS AND COMPOUNDS FOR RESTORING MUTANT P53 FUNCTION PMV Pharmaceuticals, Inc. (US) 2025-11-05 EP disclosed
US-12428406-B2 Methods and compounds for restoring mutant p53 function PMV PHARMACEUTICALS, INC. (US) 2025-09-30 US disclosed
CN-111793276-B Modified polypropylene material with high laser welding strength and preparation method thereof 万华化学(四川)有限公司 2023-12-19 CN disclosed
US-11814373-B2 Methods and compounds for restoring mutant p53 function PMV PHARMACEUTICALS, INC. (US) 2023-11-14 US disclosed
US-11814373-B2 Methods and compounds for restoring mutant p53 function PMV PHARMACEUTICALS, INC. (US) 2023-11-14 US disclosed
EP-0147758-A2 Polyesters modified with polymers of alkylene oxids The B.F. GOODRICH Company (US) 1985-07-10 EP disclosed
US-4511742-A Extraction of oligomers from polymers of epihalohydrin THE B. F. GOODRICH COMPANY (US) 1985-04-16 US disclosed
US-4508916-A Curable substituted urethane acrylates MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-04-02 US disclosed
US-4490560-A USING COLUMN OF AMORPHOUS SILICA THE B. F. GOODRICH COMPANY (US) 1984-12-25 US disclosed
EP-0107080-A1 Decolorizing polymers of epihalohydrin The B.F. GOODRICH Company (US) 1984-05-02 EP disclosed
EP-0104462-A1 Extraction of oligomers from polymers of epihalohydrin The B.F. GOODRICH Company (US) 1984-04-04 EP disclosed
EP-0103296-A2 Epihalohydrin polymers The B.F. GOODRICH Company (US) 1984-03-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260055011-A1 AMINE-BASED SOLVENTS FOR TEMPERATURE SWING SOLVENT EXTRACTION SLC6A12, SLC6A6, SLC6A9 TSHR 328/4885MAPK1 581/4885ALDH1A1 2571/4885
US-12428406-B2 Methods and compounds for restoring mutant p53 function TP53, TP53BP1, KRAS TSHR 3846/4885MAPK1 2448/4885ALDH1A1 1538/4885
US-11814373-B2 Methods and compounds for restoring mutant p53 function TP53, TP53BP1, KRAS TSHR 3846/4885MAPK1 2448/4885ALDH1A1 1538/4885
US-20260098032-A1 METHODS AND COMPOUNDS FOR RESTORING MUTANT p53 FUNCTION TP53, TP53BP1, MDM2 TSHR 2535/4885MAPK1 646/4885ALDH1A1 4027/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.