SCHEMBL8588963

SCHEMBL8588963

O=C(O)C1(Cl)C(=O)C=CC1=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2756774 0.60 GSK3A (0.40)
SCHEMBL10618506 0.57
SCHEMBL10867379 0.57 GSK3A (0.65)
SCHEMBL9354655 0.57
SCHEMBL3100736 0.57 CA1 (0.33)
SCHEMBL11038465 0.55
SCHEMBL6834812 0.55
Benzoquinone SCHEMBL31055608 0.54 ALDH1A1 (0.67)
Benzoquinone SCHEMBL27519977 0.54 ALDH1A1 (0.67)
SCHEMBL2594729 0.52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998038294-A1 GROWTH-ENHANCED TRANSGENIC PLANTS UNION CAMP CORPORATION (US) 1998-09-03 WO disclosed
US-5656422-A HYDRATING A DRIED ENZYME TO PRODUCE HYDRATED ENZYME, CONTACTING WITH SAMPLE TO DETECT PRESENCE OF PHENOLIC PRODUCTS FORMED BY CLEAVAGE OF PHENOLIC ETHER BOND BY THE ENZYME IDAHO RESEARCH FOUNDATION, INC. (US) 1997-08-12 US disclosed
US-5608147-A TRANSFORMATION; GENE EXPRESSION; GENETIC ENGINEERING; SELECTING CELL WITH 2,4-DICHLOROPHENOXYACETIC ACID NBSC, A DIVISION ON SYNOVUS BANK 1997-03-04 US disclosed
WO-1996040375-A1 ORGANIC CHEMICAL CONTAINER HAVING ATTACHED THERETO A SECOND CONTAINER FOR MICROBES CAPABLE OF DECONTAMINATING RESIDUES OF THE ORGANIC CHEMICAL IDAHO RESEARCH FOUNDATION, INC. (US) 1996-12-19 WO disclosed
EP-0738326-A1 tfdA GENE SELECTABLE MARKERS IN PLANTS AND THE USE THEREOF Union Camp Corporation (US) 1996-10-23 EP disclosed
WO-1996011283-A1 COMPOSITIONS AND METHODS FOR DETECTION OF 2,4-DICHLOROPHENOXYACETIC ACID AND RELATED COMPOUNDS IDAHO RESEARCH FOUNDATION, INC. (US) 1996-04-18 WO disclosed
WO-1995018862-A2 tfdA GENE SELECTABLE MARKERS IN PLANTS AND THE USE THEREOF UNION CAMP CORPORATION (US) 1995-07-13 WO disclosed