Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 4/20 | 0.61 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.61 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8588458 | 0.92 | ADRB1 (0.71) | ADRB2ADRB1ADRB3KCNH2SLC6A2 | |
| SCHEMBL8588612 | 0.87 | ADRB3 (0.56) | ADRB2ADRB1ADRB3KCNH2 | |
| SCHEMBL8585796 | 0.83 | ADRB3 (0.69) | ADRB2ADRB1ADRB3 | |
| SCHEMBL8585797 | 0.83 | ADRB3 (0.69) | ADRB2ADRB1ADRB3 | |
| SCHEMBL8587950 | 0.81 | ADRB3 (0.62) | ADRB2ADRB1ADRB3 | |
| SCHEMBL8587948 | 0.81 | ADRB3 (0.62) | ADRB2ADRB1ADRB3 | |
| SCHEMBL8588380 | 0.80 | ADRB3 (0.66) | ADRB2ADRB1ADRB3 | |
| SCHEMBL8588377 | 0.80 | ADRB3 (0.66) | ADRB2ADRB1ADRB3 | |
| SCHEMBL9654030 | 0.79 | ADRB1 (0.82) | ADRB2ADRB1ADRB3KCNH2SLC6A2 | |
| SCHEMBL8589604 | 0.79 | ADRB1 (0.48) | ADRB2ADRB1ADRB3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998037056-A1 | PHENOXYPROPANOLAMINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SMITHKLINE BEECHAM PLC (GB) | 1998-08-27 | — | — | WO | claimed |
| WO-1998037056-A1 | PHENOXYPROPANOLAMINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SMITHKLINE BEECHAM PLC (GB) | 1998-08-27 | — | — | WO | disclosed |