Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | TBXAS1 | P24557 | 5/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8589704 | 1.00 | CYP19A1 (0.53) | CYP19A1SMN1; SMN2TBXAS1HRH4HMOX1 | |
| SCHEMBL8588055 | 0.80 | HRH4 (0.47) | CYP19A1SMN1; SMN2TBXAS1HRH4ALDH1A1 | |
| SCHEMBL7818187 | 0.80 | HRH4 (0.59) | CYP19A1SMN1; SMN2TBXAS1HRH4HMOX1 | |
| SCHEMBL7818771 | 0.79 | TBXAS1 (0.61) | SMN1; SMN2TBXAS1HRH4HMOX1 | |
| SCHEMBL10441465 | 0.79 | IDO1 (0.53) | ALDH1A1 | |
| SCHEMBL4161005 | 0.79 | IDO1 (0.53) | ALDH1A1 | |
| SCHEMBL24295754 | 0.78 | TBXAS1 (0.63) | CYP19A1TBXAS1 | |
| SCHEMBL31754247 | 0.78 | TBXAS1 (0.63) | CYP19A1TBXAS1 | |
| Hydrochloric Acid SCHEMBL28986973 | 0.77 | IDO1 (0.52) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9073812 | 0.77 | IDO1 (0.52) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998050421-A1 | ANALGESIC PEPTIDOMIMETIC COMPOUNDS | ASTRA AKTIEBOLAG (PUBL) (SE) | 1998-11-12 | — | — | WO | disclosed |