Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | TNFRSF1A | P19438 | 4/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.57 |
| ▸ | TUBB1 | Q9H4B7 | 6/20 | 0.56 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.54 |
| ▸ | TUBB | P07437 | 3/20 | 0.54 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.54 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.54 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.54 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.54 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.54 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.54 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11539495 | 0.81 | ABCG2 (0.68) | POLBGAAABCG2TNFRSF1AABCB1 | |
| SCHEMBL374153 | 0.80 | ABCG2 (0.62) | POLBGAAABCG2TNFRSF1AABCB1 | |
| Baxitozine SCHEMBL6859777 | 0.79 | ABCG2 (0.66) | POLBGAAABCG2HPGDTNFRSF1A | |
| SCHEMBL18480640 | 0.79 | ABCG2 (0.66) | POLBGAAABCG2TNFRSF1AABCB1 | |
| Baxitozine SCHEMBL9321098 | 0.79 | ABCG2 (0.66) | POLBGAAABCG2HPGDTNFRSF1A | |
| Water SCHEMBL15135999 | 0.79 | ABCG2 (0.60) | POLBGAAABCG2TNFRSF1AABCB1 | |
| SCHEMBL14820484 | 0.78 | ABCG2 (0.84) | ABCG2TNFRSF1AABCB1TUBB1TUBB4A | |
| SCHEMBL14800858 | 0.78 | ABCG2 (0.84) | ABCG2TNFRSF1AABCB1TUBB1TUBB4A | |
| SCHEMBL17237049 | 0.77 | POLB (0.60) | POLBGAAABCG2MEN1LMNA | |
| SCHEMBL17237054 | 0.77 | POLB (0.60) | POLBGAAABCG2MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0862560-A1 | SUBSTITUTED 2-ANILINOPYRIMIDINES USEFUL AS PROTEIN KINASE INHIBITORS | CELLTECH THERAPEUTICS LIMITED (GB) | 1998-09-09 | — | — | EP | disclosed |
| WO-1997019065-A1 | SUBSTITUTED 2-ANILINOPYRIMIDINES USEFUL AS PROTEIN KINASE INHIBITORS | CELLTECH THERAPEUTICS LIMITED (GB) | 1997-05-29 | — | — | WO | disclosed |