Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.84 |
| ▸ | TNFRSF1A | P19438 | 4/20 | 0.83 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.80 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.77 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.76 |
| ▸ | TUBB | P07437 | 3/20 | 0.76 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.76 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.76 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.76 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.76 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.76 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.76 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.76 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.76 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.76 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.76 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.76 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.76 |
| ▸ | KRAS | P01116 | 4/20 | 0.75 |
| ▸ | CA1 | P00915 | 3/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14800858 | 1.00 | ABCG2 (0.84) | ABCG2TNFRSF1ATUBB1ABCB1TUBB4A | |
| SCHEMBL5960638 | 0.91 | TNFRSF1A (1.00) | ABCG2TNFRSF1ATUBB1ABCB1TUBB4A | |
| SCHEMBL5960636 | 0.91 | TNFRSF1A (1.00) | ABCG2TNFRSF1ATUBB1ABCB1TUBB4A | |
| SCHEMBL25296474 | 0.89 | ABCG2 (0.81) | ABCG2TNFRSF1AABCB1KRASCA1 | |
| SCHEMBL13480881 | 0.89 | TUBB1 (0.75) | ABCG2TNFRSF1ATUBB1ABCB1TUBB4A | |
| SCHEMBL28263079 | 0.89 | ABCG2 (0.81) | ABCG2TNFRSF1AABCB1KRASCA1 | |
| SCHEMBL31059033 | 0.89 | ABCG2 (0.68) | ABCG2TNFRSF1ATUBB1ABCB1TUBB4A | |
| SCHEMBL28984300 | 0.88 | TNFRSF1A (0.67) | ABCG2TNFRSF1ATUBB1ABCB1TUBB4A | |
| SCHEMBL11796150 | 0.87 | ABCB1 (0.83) | ABCG2TNFRSF1AABCB1KRASCA1 | |
| SCHEMBL11796142 | 0.87 | ABCB1 (0.83) | ABCG2TNFRSF1AABCB1KRASCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2878197-B1 | TISSUE PRESERVATION SOLUTION AND TISSUE PRESERVATION METHOD | UNIV OSAKA (JP) | 2018-12-26 | — | — | EP | disclosed |
| WO-2017009860-A1 | 2-BENZYL-INDANONE COMPOUNDS AS ANTICANCER AGENT AND A PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-01-19 | — | — | WO | disclosed |
| US-20150351380-A1 | TISSUE-PRESERVING LIQUID AND TISSUE-PRESERVING METHOD | OSAKA UNIVERSITY (JP) | 2015-12-10 | — | — | US | disclosed |
| EP-2878197-A1 | TISSUE-PRESERVING LIQUID AND TISSUE-PRESERVING METHOD | Osaka University (JP) | 2015-06-03 | — | — | EP | disclosed |
| US-8633242-B2 | Benzylidene indanones and processes for preparation and use thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2014-01-21 | — | — | US | disclosed |
| US-20130079396-A1 | Anticancer and Tubulin Polymerisation Inhibition Activity of Benzylidene Indanones and Process of Preparing the Same | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2013-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130079396-A1 | Anticancer and Tubulin Polymerisation Inhibition Activity of Benzylidene Indanones and Process of Preparing the Same | TUBB6, TUBB, TUBB1 | ABCG2 276/4885TNFRSF1A 3097/4885TUBB1 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.