Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.47 |
| ▸ | DPP9 | Q86TI2 | 6/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.47 |
| ▸ | DPP4 | P27487 | 4/20 | 0.47 |
| ▸ | NOD1 | Q9Y239 | 6/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSH | P09668 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | CTSC | P53634 | 1/20 | 0.39 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8592150 | 1.00 | DPP8 (0.47) | DPP8DPP9DPP7DPP4NOD1 | |
| SCHEMBL2854257 | 0.91 | DPP8 (0.51) | DPP8DPP9DPP7DPP4NOD1 | |
| SCHEMBL8495663 | 0.91 | DPP8 (0.51) | DPP8DPP9DPP7DPP4NOD1 | |
| SCHEMBL30868624 | 0.90 | DPP7 (0.54) | DPP8DPP9DPP7DPP4NOD1 | |
| SCHEMBL31244871 | 0.89 | FOLH1 (0.39) | DPP8DPP9DPP7DPP4NOD1 | |
| SCHEMBL13660260 | 0.88 | DPP8 (0.49) | DPP8DPP9DPP7DPP4NOD1 | |
| SCHEMBL31679398 | 0.83 | ACE (0.56) | DPP8DPP9DPP7DPP4NOD1 | |
| SCHEMBL29571445 | 0.83 | DPP4 (0.47) | DPP8DPP9DPP7DPP4 | |
| SCHEMBL8497101 | 0.83 | DPP7 (0.57) | DPP8DPP9DPP7DPP4NOD1 | |
| SCHEMBL29376391 | 0.83 | DPP4 (0.47) | DPP8DPP9DPP7DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998057654-A1 | METHODS FOR TREATMENT OF OCULAR NEOVASCULARIZATION | JOHNS HOPKINS UNIVERSITY (US) | 1998-12-23 | — | — | WO | disclosed |