Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.51 |
| ▸ | DPP9 | Q86TI2 | 6/20 | 0.51 |
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.51 |
| ▸ | DPP4 | P27487 | 4/20 | 0.51 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 5/20 | 0.45 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSH | P09668 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | CTSC | P53634 | 1/20 | 0.41 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8495663 | 1.00 | DPP8 (0.51) | DPP8DPP9DPP7DPP4MME | |
| SCHEMBL13660260 | 0.96 | DPP8 (0.49) | DPP8DPP9DPP7DPP4MME | |
| SCHEMBL8497101 | 0.91 | DPP7 (0.57) | DPP8DPP9DPP7DPP4NOD1 | |
| SCHEMBL8592155 | 0.91 | DPP8 (0.47) | DPP8DPP9DPP7DPP4MME | |
| SCHEMBL8592150 | 0.91 | DPP8 (0.47) | DPP8DPP9DPP7DPP4MME | |
| SCHEMBL8495650 | 0.90 | DPP4 (0.55) | DPP8DPP9DPP7DPP4NOD1 | |
| SCHEMBL17941535 | 0.90 | DPP4 (0.55) | DPP8DPP9DPP7DPP4NOD1 | |
| SCHEMBL10423708 | 0.89 | DPP9 (0.51) | DPP8DPP9DPP7DPP4MME | |
| SCHEMBL8495657 | 0.88 | DPP4 (0.54) | DPP8DPP9DPP7DPP4MME | |
| SCHEMBL10509030 | 0.87 | GNPAT (0.47) | DPP8DPP9DPP7DPP4MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7785566-B2 | Pharmaceutical compounds | GE HEALTHCARE, INC. (NO) | 2010-08-31 | — | — | US | disclosed |
| US-7763234-B2 | Pharmaceutical compounds | GE HEALTHCARE AS (NO) | 2010-07-27 | — | — | US | disclosed |
| US-20070297979-A1 | Pharmaceutical Compounds | GE HEALTHCARE AS (NO) | 2007-12-27 | — | — | US | disclosed |
| US-20070134155-A1 | Pharmaceutical compounds | AMERSHAM HEALTH AS (NO) | 2007-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070297979-A1 | Pharmaceutical Compounds | FURIN, ACE, PEPD | DPP8 22/4885DPP9 26/4885DPP7 47/4885 |
| US-20070134155-A1 | Pharmaceutical compounds | NPPA, TNNT2, PCSK9 | DPP8 1055/4885DPP9 399/4885DPP7 451/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.