SCHEMBL8592176

SCHEMBL8592176

NCC(NC1CCCCC1)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
NPC1 O15118 1/20 0.48
KMT2A Q03164 2/20 0.46
IDO1 P14902 2/20 0.45
KDM4E B2RXH2 1/20 0.44
CYP3A4 P08684 1/20 0.44
HPGD P15428 1/20 0.44
CYP2C19 P33261 1/20 0.44
RAB9A P51151 1/20 0.44
MEN1 O00255 1/20 0.43
TAAR1 Q96RJ0 3/20 0.41
EPHX1 P07099 2/20 0.41
LMNA P02545 1/20 0.41
HTR2A P28223 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28915065 0.98 GAA (0.56) GAAL3MBTL1NPC1KMT2AIDO1
SCHEMBL10625060 0.87 GAA (0.51) GAAL3MBTL1NPC1KMT2AIDO1
SCHEMBL20144711 0.83 GAA (0.54) GAAL3MBTL1NPC1KMT2AKDM4E
SCHEMBL20144687 0.81 GAA (0.56) GAAL3MBTL1NPC1KMT2AKDM4E
SCHEMBL21799675 0.77 BCHE (0.43) GAAL3MBTL1NPC1KMT2AIDO1
SCHEMBL9245326 0.77 GAA (0.59) GAAL3MBTL1NPC1KMT2AIDO1
SCHEMBL4486176 0.76 GAA (0.63) GAAL3MBTL1NPC1KMT2AIDO1
SCHEMBL16180045 0.76 GAA (0.63) GAAL3MBTL1IDO1KDM4EEPHX1
SCHEMBL14848196 0.76 GAA (0.63) GAAL3MBTL1IDO1KDM4EEPHX1
SCHEMBL10714267 0.74 GAA (0.56) GAAL3MBTL1NPC1KMT2AIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110603273-B Modified block copolymer, method for producing modified block copolymer, and resin composition 旭化成株式会社 2022-10-14 CN disclosed
US-11124593-B2 Modified block copolymer, method for producing modified block copolymer, and resin composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2021-09-21 US disclosed
US-20200199282-A1 Modified Block Copolymer, Method for Producing Modified Block Copolymer, and Resin Composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2020-06-25 US disclosed
EP-3623398-A1 MODIFIED BLOCK COPOLYMER, METHOD FOR PRODUCING MODIFIED BLOCK COPOLYMER, AND RESIN COMPOSITION Asahi Kasei Kabushiki Kaisha (JP) 2020-03-18 EP disclosed
CN-110603273-A Modified block copolymer, method for producing modified block copolymer, and resin composition 旭化成株式会社 2019-12-20 CN disclosed
EP-0613458-B1 ACYCLIC ETHYLENEDIAMINE DERIVATIVES AS SUBSTANCE P RECEPTOR ANTAGONISTS PFIZER (US) 1998-01-07 EP disclosed
US-5521220-A Acyclic ethylenediamine derivatives PFIZER INC. (US) 1996-05-28 US disclosed
EP-0613458-A1 ACYCLIC ETHYLENEDIAMINE DERIVATIVES AS SUBSTANCE P RECEPTOR ANTAGONISTS PFIZER INC. (US) 1994-09-07 EP disclosed
WO-1993010073-A1 ACYCLIC ETHYLENEDIAMINE DERIVATIVES AS SUBSTANCE P RECEPTOR ANTAGONISTS PFIZER INC. (US) 1993-05-27 WO disclosed
US-4698424-A POLYURETHANE LACQUERS BAYER AKTIENGESELLSCHAFT (DE) 1987-10-06 US disclosed