Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 9/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.49 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MGAM | O43451 | 2/20 | 0.47 |
| ▸ | SI | P14410 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20144687 | 0.98 | GAA (0.56) | GAAL3MBTL1NPC1ADRB2KMT2A | |
| SCHEMBL8084473 | 0.83 | SOS1 (0.53) | GAAL3MBTL1KCNQ3KCNQ2MGAM | |
| SCHEMBL8592176 | 0.83 | GAA (0.54) | GAAL3MBTL1NPC1KMT2AKDM4E | |
| SCHEMBL28915065 | 0.81 | GAA (0.56) | GAAL3MBTL1NPC1KMT2AKDM4E | |
| SCHEMBL10625060 | 0.80 | GAA (0.51) | GAAL3MBTL1NPC1ADRB2KMT2A | |
| SCHEMBL2092719 | 0.78 | MGAM (0.43) | NPC1KCNQ3KCNQ2MGAMSI | |
| SCHEMBL2093243 | 0.78 | MGAM (0.43) | NPC1KCNQ3KCNQ2MGAMSI | |
| SCHEMBL4486176 | 0.76 | GAA (0.63) | GAAL3MBTL1NPC1KMT2AKDM4E | |
| SCHEMBL16180045 | 0.76 | GAA (0.63) | GAAL3MBTL1KDM4E | |
| SCHEMBL14848196 | 0.76 | GAA (0.63) | GAAL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2448956-B1 | SOLID PHASE PEPTIDE SYNTHESIS OF PEPTIDE ALCOHOLS | CENTRE NAT RECH SCIENT (FR) | 2018-05-16 | — | — | EP | disclosed |