SCHEMBL85931

SCHEMBL85931

OCC(O)COCC(F)F

nearest known ligand 0.43

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.43
LMNA P02545 4/20 0.40
ALDH1A1 P00352 1/20 0.40
KDM4E B2RXH2 3/20 0.34
THRB P10828 1/20 0.33
CYP1A2 P05177 2/20 0.31
AGTR1 P30556 1/20 0.31
DUSP3 P51452 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1638881 0.86 LMNA (0.53) USP2LMNAALDH1A1KDM4ETHRB
SCHEMBL30754 0.86 LMNA (0.53) USP2LMNAALDH1A1KDM4ETHRB
Glycerin SCHEMBL2582537 0.83 LMNA (0.60) USP2LMNAALDH1A1KDM4ETHRB
SCHEMBL22279336 0.83 LMNA (0.50) USP2LMNAALDH1A1KDM4ETHRB
SCHEMBL15894238 0.83 LMNA (0.50) USP2LMNAALDH1A1KDM4ETHRB
SCHEMBL25238278 0.83 LMNA (0.50) USP2LMNAALDH1A1KDM4ETHRB
SCHEMBL10329835 0.83 LMNA (0.50) USP2LMNAALDH1A1KDM4ETHRB
SCHEMBL821029 0.83 LMNA (0.50) USP2LMNAALDH1A1KDM4ETHRB
Glycerin SCHEMBL314170 0.83 LMNA (0.60) USP2LMNAALDH1A1KDM4ETHRB
SCHEMBL6249798 0.83 LMNA (0.50) USP2LMNAALDH1A1KDM4ETHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9984715-B2 Magnetic disk and manufacturing method thereof WD Media, LLC (US) 2018-05-29 US disclosed
EP-2117725-B1 METHOD FOR FABRICATING LAMINATE NANOMOLDS LIQUIDIA TECH INC (US) 2017-10-11 EP disclosed
US-9314548-B2 Nanostructured surfaces for biomedical/biomaterial applications and processes thereof LIQUIDIA TECHNOLOGIES, INC. (US) 2016-04-19 US disclosed
WO-2015173374-A1 AROMATIC COMPOUNDS BEARING HYDROXYL-SUBSTITUTED (PER)FLUOROPOLYETHER CHAINS SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2015-11-19 WO disclosed
US-20150148903-A1 Nanostructured Surfaces for Biomedical/Biomaterial Applications and Processes Thereof LIQUIDIA TECHNOLOGIES, INC. (US) 2015-05-28 US disclosed
US-8128393-B2 Methods and materials for fabricating laminate nanomolds and nanoparticles therefrom LIQUIDIA TECHNOLOGIES, INC. (US) 2012-03-06 US disclosed
WO-2008143650-A2 METHODS AND MATERIALS FOR FABRICATING LAMINATE NANOMOLDS AND NANOPARTICLES THEREFROM LIQUIDIA TECHNOLOGIES, INC. (US) 2008-11-27 WO disclosed
US-20080131692-A1 Methods and materials for fabricating laminate nanomolds and nanoparticles therefrom LIQUIDIA TECHNOLOGIES, INC. 2008-06-05 US disclosed