Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8593174 | 1.00 | ALDH1A1 (0.50) | ALDH1A1MAPTMAOBMEN1NPC1 | |
| SCHEMBL14509132 | 0.85 | NR4A2 (0.60) | MAOBNR4A2SRD5A2GUSBPTPN1 | |
| SCHEMBL8594589 | 0.85 | MAOB (0.56) | ALDH1A1MAPTMAOBNPC1RAB9A | |
| SCHEMBL8594586 | 0.85 | MAOB (0.56) | ALDH1A1MAPTMAOBNPC1RAB9A | |
| SCHEMBL8592301 | 0.84 | F10 (0.56) | MAOBRAB9ARXFP1NR4A2SMN1; SMN2 | |
| SCHEMBL8589465 | 0.84 | ALDH1A1 (0.47) | ALDH1A1MAPTMAOBMEN1NPC1 | |
| SCHEMBL8589462 | 0.84 | ALDH1A1 (0.47) | ALDH1A1MAPTMAOBMEN1NPC1 | |
| SCHEMBL8592305 | 0.84 | F10 (0.56) | MAOBRAB9ARXFP1NR4A2SMN1; SMN2 | |
| SCHEMBL8593674 | 0.84 | MAOB (0.50) | ALDH1A1MAPTMAOBKMT2ALMNA | |
| SCHEMBL8593671 | 0.84 | MAOB (0.50) | ALDH1A1MAPTMAOBKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0658543-B1 | PROCESS FOR PRODUCING ALPHA-ALKOXYIMINOPHENYLACETONITRILE DERIVATIVE | SHIONOGI & CO (JP) | 1998-01-07 | — | — | EP | disclosed |
| EP-0658543-A1 | PROCESS FOR PRODUCING $g(a)-ALKOXYIMINOPHENYLACETONITRILE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1995-06-21 | — | — | EP | disclosed |