Ethylene

Ethylene

SCHEMBL8593493

C=C.CC(C)(C)CC(C)(C)c1ccc(O)cc1

nearest known ligand 0.91

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.91
ESR1 P03372 11/20 0.55
ESR2 Q92731 10/20 0.55
CYP3A4 P08684 5/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
LMNA P02545 1/20 0.50
TYR P14679 1/20 0.50
AR P10275 1/20 0.50
HPGD P15428 1/20 0.50
TSHR P16473 1/20 0.50
SLC6A2 P23975 1/20 0.50
SLC6A4 P31645 1/20 0.50
HTR6 P50406 1/20 0.50
ESRRG P62508 1/20 0.50
SLC6A3 Q01959 1/20 0.50
HSD17B10 Q99714 1/20 0.50
CYP2D6 P10635 1/20 0.44
HIF1A Q16665 1/20 0.44
ALDH1A1 P00352 2/20 0.43
MEN1 O00255 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10141 0.96 SHBG (1.00) SHBGESR1ESR2CYP3A4SMN1; SMN2
SCHEMBL31282065 0.96 SHBG (1.00) SHBGESR1ESR2CYP3A4SMN1; SMN2
Formaldehyde SCHEMBL290371 0.94 SHBG (0.88) SHBGESR1ESR2CYP3A4SMN1; SMN2
Hydrogen Sulfide SCHEMBL10824257 0.93 SHBG (0.95) SHBGESR1ESR2CYP3A4SMN1; SMN2
SCHEMBL22773183 0.93 SHBG (0.95) SHBGESR1ESR2CYP3A4SMN1; SMN2
SCHEMBL10785821 0.93 SHBG (0.95) SHBGESR1ESR2CYP3A4SMN1; SMN2
Formaldehyde SCHEMBL28440479 0.92 SHBG (0.84) SHBGESR1ESR2CYP3A4SMN1; SMN2
Benzene SCHEMBL29025935 0.91 SHBG (0.91) SHBGESR1ESR2CYP3A4SMN1; SMN2
SCHEMBL7063934 0.89 SHBG (0.88) SHBGESR1ESR2CYP3A4SMN1; SMN2
SCHEMBL647964 0.89 SHBG (0.88) SHBGESR1ESR2CYP3A4SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998002582-A9 METHODS FOR DETECTING AND AMPLIFYING NUCLEIC ACID SEQUENCES USING MODIFIED OLIGONUCLEOTIDES HAVING INCREASED TARGET SPECIFIC T¿M? 1998-05-28 WO disclosed