Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 4/20 | 0.35 |
| ▸ | THRB | P10828 | 6/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 5/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8594873 | 1.00 | RARB (0.36) | RARBFAAHALDH1A1MEN1KMT2A | |
| SCHEMBL8593256 | 1.00 | RARB (0.36) | RARBFAAHALDH1A1MEN1KMT2A | |
| SCHEMBL8593426 | 0.95 | FAAH (0.35) | RARBFAAHALDH1A1MEN1KMT2A | |
| SCHEMBL8591682 | 0.95 | FAAH (0.35) | RARBFAAHALDH1A1MEN1KMT2A | |
| SCHEMBL8592743 | 0.95 | FAAH (0.35) | RARBFAAHALDH1A1MEN1KMT2A | |
| SCHEMBL8594914 | 0.95 | FAAH (0.35) | RARBFAAHALDH1A1MEN1KMT2A | |
| SCHEMBL8591548 | 0.95 | FAAH (0.35) | RARBFAAHALDH1A1MEN1KMT2A | |
| SCHEMBL8595823 | 0.92 | FAAH (0.36) | RARBFAAHALDH1A1MEN1KMT2A | |
| SCHEMBL8591642 | 0.92 | FAAH (0.36) | RARBFAAHALDH1A1MEN1KMT2A | |
| SCHEMBL8591617 | 0.92 | FAAH (0.36) | RARBFAAHALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537620-B1 | Nitrogen-containing heterorings | ROLIC AG (CH) | 1998-01-07 | — | — | EP | disclosed |
| EP-0537620-A1 | Nitrogen-containing heterorings | F. HOFFMANN-LA ROCHE AG (CH) | 1993-04-21 | — | — | EP | disclosed |