Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.71 |
| ▸ | MAPT | P10636 | 5/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | POLB | P06746 | 4/20 | 0.71 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.71 |
| ▸ | RECQL | P46063 | 3/20 | 0.71 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.71 |
| ▸ | EIF4E | P06730 | 1/20 | 0.71 |
| ▸ | EIF4G1 | Q04637 | 1/20 | 0.71 |
| ▸ | THRB | P10828 | 1/20 | 0.71 |
| ▸ | ATM | Q13315 | 1/20 | 0.66 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.63 |
| ▸ | MAP3K5 | Q99683 | 3/20 | 0.62 |
| ▸ | APEX1 | P27695 | 1/20 | 0.62 |
| ▸ | SYK | P43405 | 1/20 | 0.61 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8594645 | 1.00 | MEN1 (0.71) | MEN1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL3132319 | 0.90 | MAPT (0.73) | MEN1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL3132334 | 0.90 | MAPT (0.73) | MEN1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL3132328 | 0.90 | MAPT (0.73) | MEN1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL3892304 | 0.89 | APEX1 (0.79) | MEN1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL29701307 | 0.89 | APEX1 (0.79) | MEN1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL3892300 | 0.89 | APEX1 (0.79) | MEN1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL3890923 | 0.86 | MAP3K5 (0.70) | MEN1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL3890920 | 0.86 | MAP3K5 (0.70) | MEN1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL8289174 | 0.86 | MAP3K5 (0.70) | MEN1KMT2AMAPTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998053790-A2 | COMPOUNDS THAT INHIBIT THE BINDING OF VASCULAR ENDOTHELIAL GROWTH FACTOR TO ITS RECEPTORS | TEXAS BIOTECHNOLOGY CORPORATION (US) | 1998-12-03 | — | — | WO | claimed |