Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.73 |
| ▸ | MEN1 | O00255 | 4/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.73 |
| ▸ | RECQL | P46063 | 3/20 | 0.73 |
| ▸ | LMNA | P02545 | 3/20 | 0.73 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.73 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.73 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.72 |
| ▸ | POLB | P06746 | 4/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.72 |
| ▸ | EIF4E | P06730 | 1/20 | 0.72 |
| ▸ | EIF4G1 | Q04637 | 1/20 | 0.72 |
| ▸ | THRB | P10828 | 1/20 | 0.72 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.72 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | SYK | P43405 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | EP300 | Q09472 | 1/20 | 0.66 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3132319 | 1.00 | MAPT (0.73) | MAPTALDH1A1MEN1KMT2ARECQL | |
| SCHEMBL3132328 | 1.00 | MAPT (0.73) | MAPTALDH1A1MEN1KMT2ARECQL | |
| SCHEMBL19021494 | 0.92 | MEN1 (0.73) | MAPTALDH1A1MEN1KMT2ARECQL | |
| SCHEMBL22240435 | 0.92 | MEN1 (0.68) | MAPTALDH1A1MEN1KMT2ARECQL | |
| SCHEMBL23145046 | 0.91 | STAT3 (0.76) | MAPTALDH1A1MEN1KMT2ARECQL | |
| SCHEMBL46211 | 0.91 | STAT3 (0.76) | MAPTALDH1A1MEN1KMT2ARECQL | |
| SCHEMBL18301010 | 0.91 | STAT3 (0.76) | MAPTALDH1A1MEN1KMT2ARECQL | |
| SCHEMBL6092742 | 0.90 | MEN1 (0.66) | MAPTALDH1A1MEN1KMT2ARECQL | |
| SCHEMBL8594643 | 0.90 | MEN1 (0.71) | MAPTALDH1A1MEN1KMT2ARECQL | |
| SCHEMBL4408844 | 0.90 | EP300 (0.82) | MAPTALDH1A1MEN1KMT2ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120219613-A1 | Novel Antiviral Agents for Enveloped Viruses | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-08-30 | — | — | US | claimed |
| WO-2010044924-A1 | NOVEL ANTIVIRAL AGENTS FOR ENVELOPED VIRUSES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-04-22 | — | — | WO | claimed |
| US-20120219613-A1 | Novel Antiviral Agents for Enveloped Viruses | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-08-30 | — | — | US | disclosed |
| WO-2010044924-A1 | NOVEL ANTIVIRAL AGENTS FOR ENVELOPED VIRUSES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-04-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120219613-A1 | Novel Antiviral Agents for Enveloped Viruses | MAVS, LAMP1, HAVCR2 | MAPT 3126/4885ALDH1A1 1264/4885MEN1 4512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.