Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 3/20 | 0.55 |
| ▸ | PSMG3 | Q9BT73 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | SLC37A4 | O43826 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8591659 | 0.92 | PLA2G2A (0.56) | PLA2G2APSMG3IDO1SLC37A4LMNA | |
| SCHEMBL8591712 | 0.90 | PLA2G2A (0.50) | PLA2G2APSMG3IDO1SLC37A4L3MBTL1 | |
| SCHEMBL8625617 | 0.86 | PLA2G2A (0.48) | PLA2G2APSMG3IDO1SLC37A4SMN1; SMN2 | |
| SCHEMBL8591931 | 0.84 | PLA2G2A (0.50) | PLA2G2APSMG3IDO1SLC37A4MAPT | |
| SCHEMBL8591400 | 0.83 | PLA2G2A (0.59) | PLA2G2APSMG3IDO1SLC37A4LMNA | |
| SCHEMBL8594685 | 0.82 | PLA2G2A (0.53) | PLA2G2APSMG3IDO1SLC37A4LMNA | |
| SCHEMBL8593578 | 0.82 | PLA2G2A (0.53) | PLA2G2APSMG3IDO1SLC37A4LMNA | |
| SCHEMBL8594227 | 0.82 | PLA2G2A (0.55) | PLA2G2APSMG3IDO1SLC37A4MAPK1 | |
| SCHEMBL8592611 | 0.81 | PLA2G2A (0.55) | PLA2G2APSMG3IDO1SLC37A4MAPT | |
| SCHEMBL8594572 | 0.81 | PLA2G2A (0.53) | PLA2G2APSMG3IDO1SLC37A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0646569-B1 | Novel carboxylate derivatives exhibiting phospholipase A2 inhibitory activity | SHIONOGI & CO (JP) | 1998-01-07 | — | — | EP | disclosed |
| EP-0646569-A1 | Novel carboxylate derivatives exhibiting phospholipase A2 inhibitory activity | SHIONOGI & CO., LTD. (JP) | 1995-04-05 | — | — | EP | disclosed |