Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.82 |
| ▸ | PKM | P14618 | 2/20 | 0.82 |
| ▸ | LMNA | P02545 | 2/20 | 0.82 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.82 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.82 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6675598 | 1.00 | ALDH1A1 (0.82) | ALDH1A1PKMLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL4060764 | 0.98 | ALDH1A1 (0.79) | ALDH1A1PKMLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL812738 | 0.93 | ALDH1A1 (0.75) | ALDH1A1PKMLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL21048464 | 0.91 | ALDH1A1 (1.00) | ALDH1A1PKMLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL9577143 | 0.91 | ALDH1A1 (1.00) | ALDH1A1PKMLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL12672471 | 0.91 | ALDH1A1 (1.00) | ALDH1A1PKMLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL8349699 | 0.91 | ALDH1A1 (1.00) | ALDH1A1PKMLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL2004233 | 0.90 | ALDH1A1 (0.67) | ALDH1A1PKMLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL2009617 | 0.90 | ALDH1A1 (0.67) | ALDH1A1PKMLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL10453840 | 0.89 | ALDH1A1 (0.96) | ALDH1A1PKMLMNAKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998053790-A2 | COMPOUNDS THAT INHIBIT THE BINDING OF VASCULAR ENDOTHELIAL GROWTH FACTOR TO ITS RECEPTORS | TEXAS BIOTECHNOLOGY CORPORATION (US) | 1998-12-03 | — | — | WO | claimed |