Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | MGLL | Q99685 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.36 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1585999 | 0.71 | MAPT (0.44) | ALDH1A1RAB9AMAPTSMN1; SMN2GAA | |
| SCHEMBL253209 | 0.68 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP2D6CYP2C19SETD7 | |
| SCHEMBL10613637 | 0.67 | PTGS1 (0.53) | ALDH1A1SETD7MAPTMEN1KMT2A | |
| SCHEMBL27608028 | 0.67 | ALDH1A1 (0.41) | ALDH1A1NPC1RAB9AMAPTMEN1 | |
| SCHEMBL5323524 | 0.66 | CES1 (0.53) | ALDH1A1SETD7MAPTMEN1KMT2A | |
| SCHEMBL9830527 | 0.66 | SETD7 (0.38) | ALDH1A1CYP1A2CYP2D6CYP2C19SETD7 | |
| SCHEMBL9161505 | 0.65 | HDAC3 (0.59) | ALDH1A1CYP1A2CYP2D6CYP2C19SETD7 | |
| SCHEMBL21571464 | 0.65 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP2D6CYP2C19SETD7 | |
| SCHEMBL29013458 | 0.64 | GAA (0.44) | MAPTGAA | |
| SCHEMBL1961830 | 0.64 | HDAC3 (0.61) | ALDH1A1CYP1A2CYP2D6CYP2C19SETD7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786460-A3 | 2-Arylquinolines and process for producing the same | ASAHI GLASS COMPANY LTD. (JP) | 1998-06-17 | — | — | EP | disclosed |
| EP-0786460-A2 | 2-Arylquinolines and process for producing the same | ASAHI GLASS COMPANY LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |