Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 6/20 | 0.49 |
| ▸ | ELANE | P08246 | 2/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.44 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PLG | P00747 | 3/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8597589 | 1.00 | F2 (0.49) | F2ELANEPRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL8599728 | 0.99 | F2 (0.48) | F2ELANEPRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL11269343 | 0.99 | F2 (0.48) | F2ELANEPRSS1PRSS2PRSS3 | |
| SCHEMBL6393669 | 0.96 | F2 (0.46) | F2ELANEPRSS1PRSS2PRSS3 | |
| SCHEMBL6403908 | 0.92 | F2 (0.43) | F2ELANEPRSS1PRSS2PRSS3 | |
| SCHEMBL8597584 | 0.90 | ELANE (0.66) | F2ELANEPRSS1PRSS2PRSS3 | |
| SCHEMBL8595417 | 0.90 | ELANE (0.66) | F2ELANEPRSS1PRSS2PRSS3 | |
| SCHEMBL8597673 | 0.89 | ELANE (0.45) | F2ELANEPRSS1PRSS2PRSS3 | |
| SCHEMBL8597670 | 0.89 | ELANE (0.45) | F2ELANEPRSS1PRSS2PRSS3 | |
| SCHEMBL8596951 | 0.89 | ELANE (0.49) | F2ELANESMN1; SMN2HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585130-B1 | External preparation for skin containing a depigmentation agent | SHISEIDO CO LTD (JP) | 1998-01-28 | — | — | EP | disclosed |
| US-5690914-A | TRANEXAMIC ACID DERIVATIVES FOR DEPIGMENTATION | SHISEIDO CO., LTD (JP) | 1997-11-25 | — | — | US | disclosed |
| EP-0585130-A2 | External preparation for skin containing a depigmentation agent | SHISEIDO COMPANY LIMITED (JP) | 1994-03-02 | — | — | EP | disclosed |