Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.45 |
| ▸ | F2 | P00734 | 4/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.43 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8597673 | 1.00 | ELANE (0.45) | ELANEF2PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL11286959 | 0.99 | ELANE (0.44) | ELANEF2PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL11286962 | 0.99 | ELANE (0.44) | ELANEF2PRSS1PRSS2PRSS3 | |
| SCHEMBL8597586 | 0.89 | F2 (0.49) | ELANEF2PRSS1PRSS2PRSS3 | |
| SCHEMBL8597589 | 0.89 | F2 (0.49) | ELANEF2PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL11277236 | 0.88 | ELANE (0.43) | ELANEF2PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL11277234 | 0.88 | ELANE (0.43) | ELANEF2PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL11269343 | 0.88 | F2 (0.48) | ELANEF2PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL8599728 | 0.88 | F2 (0.48) | ELANEF2PRSS1PRSS2PRSS3 | |
| SCHEMBL8598845 | 0.88 | MMP13 (0.45) | ELANEF2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585130-B1 | External preparation for skin containing a depigmentation agent | SHISEIDO CO LTD (JP) | 1998-01-28 | — | — | EP | disclosed |
| US-5690914-A | TRANEXAMIC ACID DERIVATIVES FOR DEPIGMENTATION | SHISEIDO CO., LTD (JP) | 1997-11-25 | — | — | US | disclosed |
| EP-0585130-A2 | External preparation for skin containing a depigmentation agent | SHISEIDO COMPANY LIMITED (JP) | 1994-03-02 | — | — | EP | disclosed |