⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12401592 | 0.82 | — | — | |
| SCHEMBL28548869 | 0.76 | — | — | |
| SCHEMBL2100842 | 0.70 | — | — | |
| SCHEMBL30519219 | 0.70 | — | — | |
| SCHEMBL26618236 | 0.70 | — | — | |
| SCHEMBL28628072 | 0.67 | — | — | |
| SCHEMBL3764421 | 0.67 | ALDH1A1 (0.55) | — | |
| SCHEMBL1319 | 0.65 | — | — | |
| SCHEMBL17331 | 0.65 | — | — | |
| SCHEMBL15658212 | 0.65 | ALDH1A1 (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0654544-B1 | Process for lining a chemical reactor with silicon-based ceramic materials by thermal decomposition of silazane precursors | ENICHEM SPA (IT) | 1998-01-28 | — | — | EP | claimed |
| EP-0671483-B1 | Method for vapor deposition of a ceramic coating using a steam-containing carrier gas and non-alkoxy silane precursors | ENICHEM SPA (IT) | 1997-12-29 | — | — | EP | claimed |
| CN-112300208-B | Preparation method of cyclodisilazane | 中国科学院化学研究所 | 2022-03-01 | — | — | CN | disclosed |
| CN-112300208-A | Preparation method of cyclodisilazane | 中国科学院化学研究所 | 2021-02-02 | — | — | CN | disclosed |
| CN-106317101-B | A kind of method of non high temperature exchange process synthesis 1,3- bis- (diphenyl chlorosilane base) -2,2,4,4- tetramethyl-ring disilazane | 中国科学院化学研究所 | 2019-01-22 | — | — | CN | disclosed |
| CN-106317102-B | A kind of synthetic method of bis- (diphenyl chlorosilane base) -2,2,4,4- tetramethyl-ring disilazanes of 1,3- | 中国科学院化学研究所 | 2018-07-13 | — | — | CN | disclosed |
| CN-106317101-A | Method for synthesizing 1,3-di(diphenylchlorosilyl)-2,2,4,4-tetramethylcyclodisilazane by non-high-temperature exchange process | 中国科学院化学研究所 | 2017-01-11 | — | — | CN | disclosed |
| EP-0654544-B1 | Process for lining a chemical reactor with silicon-based ceramic materials by thermal decomposition of silazane precursors | ENICHEM SPA (IT) | 1998-01-28 | — | — | EP | disclosed |
| US-5616754-A | ORGANO DISILAZANE OR TRISILAZANE CHEMICAL INTERMEDIATES | ENICHEM S.P.A. (IT) | 1997-04-01 | — | — | US | disclosed |
| EP-0654544-A2 | Compounds useful as chemical precursors in chemical vapor deposition of silicon-based ceramic materials | ENICHEM S.p.A. (IT) | 1995-05-24 | — | — | EP | disclosed |
| US-5413813-A | Pyrolysis of compounds to form ceramics | ENICHEM S.P.A. (IT) | 1995-05-09 | — | — | US | disclosed |