Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 2/20 | 0.31 |
| ▸ | GABRD | O14764 | 2/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.31 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.31 |
| ▸ | GABRE | P78334 | 2/20 | 0.31 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.31 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL727977 | 0.80 | MAPT (0.35) | MEN1ALDH1A1KMT2A | |
| SCHEMBL727974 | 0.77 | PLA2G2C (0.42) | MEN1ALDH1A1THRBKMT2A | |
| SCHEMBL1303463 | 0.76 | AKR1B1 (0.41) | CYP1A2MEN1ALDH1A1KMT2A | |
| SCHEMBL6503000 | 0.75 | TSHR (0.37) | ALDH1A1 | |
| SCHEMBL9272109 | 0.74 | — | — | |
| SCHEMBL5614208 | 0.73 | GPR84 (0.46) | CYP1A2MEN1ALDH1A1KMT2A | |
| SCHEMBL9067463 | 0.73 | GPR84 (0.46) | CYP1A2MEN1ALDH1A1KMT2A | |
| SCHEMBL2142717 | 0.73 | CYP1A2 (0.43) | CYP1A2MEN1ALDH1A1THRBKMT2A | |
| SCHEMBL1302163 | 0.72 | AKR1B1 (0.36) | CYP1A2MEN1ALDH1A1THRBKMT2A | |
| SCHEMBL727980 | 0.72 | AKR1B1 (0.38) | MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4048104-A | Polyisocyanate prepolymers from scrap polyester and polyurethane foam products obtained therefrom | FREEMAN CHEMICAL CORPORATION (US) | 1977-09-13 | — | — | US | claimed |
| EP-0821019-A1 | Process for the preparation of polyurethane rigid foams | BASF AKTIENGESELLSCHAFT (DE) | 1998-01-28 | — | — | EP | disclosed |
| US-4417001-A | POLYOL IS DIGESTION PRODUCT OF POLYALKYLENE TEREPHTHALATE IN ORGANIC POLYOL | FREEMAN CHEMICAL CORPORATION (US) | 1983-11-22 | — | — | US | disclosed |
| US-4048104-A | Polyisocyanate prepolymers from scrap polyester and polyurethane foam products obtained therefrom | FREEMAN CHEMICAL CORPORATION (US) | 1977-09-13 | — | — | US | disclosed |