Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.67 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.61 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.61 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.61 |
| ▸ | PLG | P00747 | 3/20 | 0.57 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.57 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.57 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.57 |
| ▸ | PLAU | P00749 | 1/20 | 0.57 |
| ▸ | PRCP | P42785 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8628590 | 1.00 | NAAA (0.67) | NAAAGNAI3GNAO1GNAI1PLG | |
| SCHEMBL8598695 | 1.00 | NAAA (0.67) | NAAAGNAI3GNAO1GNAI1PLG | |
| SCHEMBL8628588 | 1.00 | NAAA (0.67) | NAAAGNAI3GNAO1GNAI1PLG | |
| Hydrochloric Acid SCHEMBL8596361 | 0.98 | NAAA (0.65) | NAAAGNAI3GNAO1GNAI1PLG | |
| Hydrochloric Acid SCHEMBL3786602 | 0.98 | NAAA (0.65) | NAAAGNAI3GNAO1GNAI1PLG | |
| Hydrochloric Acid SCHEMBL8594864 | 0.98 | NAAA (0.65) | NAAAGNAI3GNAO1GNAI1PLG | |
| Hydrochloric Acid SCHEMBL8596363 | 0.98 | NAAA (0.65) | NAAAGNAI3GNAO1GNAI1PLG | |
| SCHEMBL8594845 | 0.95 | NAAA (0.58) | NAAAGNAI3GNAO1GNAI1PLG | |
| SCHEMBL8594847 | 0.95 | NAAA (0.58) | NAAAGNAI3GNAO1GNAI1PLG | |
| Hydrochloric Acid SCHEMBL8599841 | 0.94 | NAAA (0.57) | NAAAGNAI3GNAO1GNAI1PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585130-B1 | External preparation for skin containing a depigmentation agent | SHISEIDO CO LTD (JP) | 1998-01-28 | — | — | EP | disclosed |
| US-5690914-A | TRANEXAMIC ACID DERIVATIVES FOR DEPIGMENTATION | SHISEIDO CO., LTD (JP) | 1997-11-25 | — | — | US | disclosed |
| EP-0585130-A2 | External preparation for skin containing a depigmentation agent | SHISEIDO COMPANY LIMITED (JP) | 1994-03-02 | — | — | EP | disclosed |