Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 18/20 | 1.00 |
| ▸ | HTR2A | P28223 | 14/20 | 1.00 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8595714 | 1.00 | HTR2C (1.00) | HTR2CHTR2AHTR2BMETAP1 | |
| SCHEMBL8595428 | 1.00 | HTR2C (1.00) | HTR2CHTR2AHTR2BMETAP1 | |
| SCHEMBL8598052 | 0.92 | HTR2C (1.00) | HTR2CHTR2AHTR2BMETAP1 | |
| SCHEMBL8598048 | 0.92 | HTR2C (1.00) | HTR2CHTR2AHTR2BMETAP1 | |
| Fumaric Acid SCHEMBL8874759 | 0.90 | HTR2C (0.81) | HTR2CHTR2AMETAP1 | |
| Fumaric Acid SCHEMBL8874755 | 0.90 | HTR2C (0.81) | HTR2CHTR2AMETAP1 | |
| Fumaric Acid SCHEMBL8875709 | 0.90 | HTR2C (0.81) | HTR2CHTR2AMETAP1 | |
| Fumaric Acid SCHEMBL8873435 | 0.90 | HTR2C (0.81) | HTR2CHTR2AMETAP1 | |
| Fumaric Acid SCHEMBL8875714 | 0.90 | HTR2C (0.81) | HTR2CHTR2AMETAP1 | |
| Fumaric Acid SCHEMBL8873443 | 0.90 | HTR2C (0.81) | HTR2CHTR2AMETAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7172867-B2 | Methods of testing for allergic diseases, and therapeutic agents for treating same | GENOX RESEARCH, INC. (JP) | 2007-02-06 | — | — | US | disclosed |
| US-7172867-B2 | Methods of testing for allergic diseases, and therapeutic agents for treating same | GENOX RESEARCH, INC. (JP) | 2007-02-06 | — | — | US | disclosed |
| EP-0657426-B1 | Tricyclic pyrrole derivatives | HOFFMANN LA ROCHE (CH) | 1998-07-22 | — | — | EP | disclosed |
| EP-0657426-A2 | Tricyclic pyrrole derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1995-06-14 | — | — | EP | disclosed |