SCHEMBL8599064

SCHEMBL8599064

CCN(CC)CC1CCC(C(=O)O)CC1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLG P00747 1/20 0.50
PLAT P00750 1/20 0.50
LMNA P02545 1/20 0.50
ANPEP P15144 1/20 0.41
ENPEP Q07075 1/20 0.41
TAS2R14 Q9NYV8 12/20 0.40
ALDH1A1 P00352 2/20 0.38
PKM P14618 1/20 0.38
ALOX5 P09917 1/20 0.36
CA2 P00918 1/20 0.36
MEN1 O00255 1/20 0.36
CYP2C9 P11712 1/20 0.36
KMT2A Q03164 1/20 0.36
GABRP O00591 1/20 0.35
GABRD O14764 1/20 0.35
GABRA1 P14867 1/20 0.35
TSHR P16473 1/20 0.35
GABRB1 P18505 1/20 0.35
GABRG2 P18507 1/20 0.35
GABRB3 P28472 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8597951 1.00 PLG (0.50) PLGPLATLMNAANPEPENPEP
Hydrochloric Acid SCHEMBL8596240 0.98 PLG (0.48) PLGPLATLMNAANPEPENPEP
Hydrochloric Acid SCHEMBL8597570 0.98 PLG (0.48) PLGPLATLMNAANPEPENPEP
SCHEMBL20794416 0.86 PLG (0.42) PLGPLATLMNAANPEPENPEP
Cyclopropane Carboxylic Acid SCHEMBL27744624 0.85 LMNA (0.48) PLGPLATLMNAANPEPENPEP
SCHEMBL18031062 0.82 PLG (0.48) PLGPLATLMNAANPEPENPEP
SCHEMBL14183042 0.80
SCHEMBL8595548 0.79 PLG (0.46) PLGPLATLMNAANPEPENPEP
SCHEMBL8595553 0.79 PLG (0.46) PLGPLATLMNAANPEPENPEP
SCHEMBL8594835 0.79 PLG (0.54) PLGPLATLMNAANPEPENPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0585130-B1 External preparation for skin containing a depigmentation agent SHISEIDO CO LTD (JP) 1998-01-28 EP disclosed
US-5690914-A TRANEXAMIC ACID DERIVATIVES FOR DEPIGMENTATION SHISEIDO CO., LTD (JP) 1997-11-25 US disclosed
EP-0585130-A2 External preparation for skin containing a depigmentation agent SHISEIDO COMPANY LIMITED (JP) 1994-03-02 EP disclosed