Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | APAF1 | O14727 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6000327 | 0.84 | PTPN1 (1.00) | PTPN1SMN1; SMN2HTTCA2PTPN11 | |
| SCHEMBL6001787 | 0.84 | PTPN1 (1.00) | PTPN1SMN1; SMN2HTTCA2PTPN11 | |
| SCHEMBL6001500 | 0.81 | PTPN1 (0.86) | PTPN1SMN1; SMN2HTTCA2PTPN11 | |
| SCHEMBL6000356 | 0.78 | PTPN1 (0.81) | PTPN1SMN1; SMN2HTTCA2PTPN11 | |
| SCHEMBL8599205 | 0.75 | SMN1; SMN2 (0.44) | PTPN1SMN1; SMN2LMNATSHRHTT | |
| SCHEMBL6000251 | 0.74 | PTPN1 (0.69) | PTPN1SMN1; SMN2LMNACA2PTPN11 | |
| SCHEMBL6001776 | 0.74 | PTPN1 (0.69) | PTPN1SMN1; SMN2LMNACA2PTPN11 | |
| SCHEMBL6000296 | 0.74 | PTPN1 (0.63) | PTPN1SMN1; SMN2LMNACA2PTPN11 | |
| SCHEMBL15116359 | 0.74 | PTPN1 (0.73) | PTPN1SMN1; SMN2LMNACA2PTPN11 | |
| SCHEMBL6428635 | 0.74 | PTPN1 (0.73) | PTPN1SMN1; SMN2CA2PTPN11MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8193011-A | — | — | None | — | — | JP | disclosed |
| JP-10025213-A | — | — | None | — | — | JP | disclosed |
| JP-H1025213-A | HERBICIDAL COMPOSITION COMPRISING SULFONAMIDE DERIVATIVE AND PRETILACHLOR | SANKYO CO LTD | 1998-01-27 | — | — | JP | disclosed |
| JP-H08193011-A | HERBICIDAL SULFONAMIDE COMPOUND | SANKYO CO LTD | 1996-07-30 | — | — | JP | disclosed |