Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19766978 | 0.77 | KDM4E (0.31) | KDM4E | |
| SCHEMBL5046887 | 0.72 | — | — | |
| SCHEMBL57008 | 0.70 | — | — | |
| SCHEMBL11460932 | 0.69 | DAO (0.32) | — | |
| SCHEMBL20368071 | 0.68 | — | — | |
| SCHEMBL4456405 | 0.68 | MAPT (0.37) | MAPTKDM4ETP53MAPK1CYP2C19 | |
| SCHEMBL18920925 | 0.67 | MAPT (0.35) | MAPTKDM4ETP53MAPK1CYP2C19 | |
| SCHEMBL15681798 | 0.65 | MAPT (0.30) | MAPTKDM4ETP53MAPK1CYP2C19 | |
| SCHEMBL891666 | 0.65 | MAPT (0.30) | MAPTKDM4ETP53MAPK1CYP2C19 | |
| Acetic Acid SCHEMBL10426873 | 0.64 | MAPT (0.33) | MAPTKDM4ETP53MAPK1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532120-B1 | Process for the preparation of 4-hydroxy-3(2H)furanones | TASTEMAKER BV (NL) | 1998-01-07 | — | — | EP | disclosed |
| EP-0532120-A1 | Process for the preparation of 4-hydroxy-3(2H)furanones | Tastemaker B.V. (NL) | 1993-03-17 | — | — | EP | disclosed |